pemirolast

Known as: PERMIROLAST, 9-methyl-3-(1H-tetrazol-5-yl)-4H-pyrido(1,2-a)pyrimidin-4-one, pemirolast [Chemical/Ingredient] 
A pyrimidinone derivative with anti-allergic activity. Pemirolast blocks the antigen-mediated calcium ion influx into mast cells. This prevents mast… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2015
02419822015

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2011
2011
Emesis is the most feared side effect in patients who are undergoing cancer chemotherapy. In particular, cisplatin causes severe… (More)
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2005
2005
The effect of the simultaneous use of 0.025% levocabastine hydrochloride eye drops (levocabastine) and 0.1% pemirolast potassium… (More)
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2004
2004
We compared the efficacy of a new nonsteroidal antiinflammatory drug (NSAID) eye drop, 0.1% bromfenac sodium (Bromfenac), with… (More)
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2004
2004
The effects of anti-allergic agents on the hypersensitivity reactions to paclitaxel, an anti-cancer agent, were examined in rats… (More)
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2000
2000
AS-35, (9-[4-acetyl-3-hydroxy-2-n-propylphenoxy) methyl]-3-(1H-tetrazol-5-yl)-4H-pyrido[1, 2-a] pyrimidin-4-one), was developed… (More)
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1998
1998
BACKGROUND We recently confirmed that pemirolast potassium, an antiallergic agent, markedly inhibits migration and proliferation… (More)
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1997
1997
We previously reported that tranilast, an antiallergic agent, reduced intimal thickening after endothelial injury in rats. In… (More)
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1997
1997
BACKGROUND The concept of mast cell heterogeneity is well established. Recent data indicate that human conjunctival tissue mast… (More)
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1992
1992
Pemirolast is a new oral, nonbronchodilator antiallergy medication that is being evaluated for the therapy of asthma. In this… (More)
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1991
1991
The effects of a potent antiallergic drug, pemirolast (TBX), on activation of signal-transducing phospholipase C and A2, were… (More)
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