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pateamine A

 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Cachexia, or muscle-wasting syndrome, is one of the major causes of death in patients affected by diseases such as cancer, AIDS… Expand
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Highly Cited
2010
Highly Cited
2010
Angiogenin (ANG) is a secreted ribonuclease that cleaves tRNA to initiate a stress-response program in mammalian cells. Here we… Expand
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Highly Cited
2009
Highly Cited
2009
We report here that des-methyl, des-amino pateamine A (DMDA-PatA), a structurally simplified analogue of the marine natural… Expand
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2009
2009
Nonsense-mediated mRNA decay (NMD) in mammalian cells is a key mechanism for the removal of mRNA containing premature stop codons… Expand
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2007
2007
Central to cap-dependent eukaryotic translation initiation is the eIF4F complex, which is composed of the three eukaryotic… Expand
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Highly Cited
2006
Highly Cited
2006
Stress granules are aggregates of small ribosomal subunits, mRNA, and numerous associated RNA-binding proteins that include… Expand
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Highly Cited
2006
Highly Cited
2006
Eukaryotic initiation factor 4A (eIF4A) is a member of the DEAD-box family of putative RNA helicases whose members are involved… Expand
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Highly Cited
2005
Highly Cited
2005
Translation initiation in eukaryotes is accomplished through the coordinated and orderly action of a large number of proteins… Expand
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2004
2004
Pateamine A (PatA), a marine metabolite from Mycale sp., is a potent inhibitor of the intracellular signal transduction pathway… Expand
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Highly Cited
1998
Highly Cited
1998
The asymmetric synthesis of the potent immunosuppressive agent (−)-pateamine A isolated from the marine sponge Mycale sp. is… Expand
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