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paraconic acid

National Institutes of Health

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Broader (1)

4-Butyrolactone
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Stereodivergent Synthesis of Chiral Paraconic Acids via Dynamic Kinetic Resolution of 3-Acylsuccinimides.
A direct N-heterocyclic carbene (NHC) catalysis of maleimides with alkyl aldehydes is established for the synthesis of 3… Expand
2017
2017
Rh(II)-Catalyzed Cyclopropanation of Furans and Its Application to the Total Synthesis of Natural Product Derivatives.
Rh(II)-catalyzed enantioselective cyclopropanations of furans, providing access to synthetically useful building blocks, are… Expand
2014
2014
Straightforward enantioselective access to γ-butyrolactones bearing an all-carbon β-quaternary stereocenter.
An enantioselective one-pot aldol/lactonization sequence has been developed to access highly challenging γ-butyrolactones bearing… Expand
2012
2012
Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres.
A new, highly enantio- and diastereoselective catalytic asymmetric formal cycloaddition of aryl succinic anhydrides and aldehydes… Expand
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  • table 2
2011
2011
Synthesis and cytotoxic evaluation of novel paraconic acid analogs.
A novel class of 2,3-tri- and tetrasubstituted γ-butyrolactones analogous to paraconic acids has been synthesized in one step… Expand
  • table 1
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  • table 2
  • table 3
Highly Cited
2005
Highly Cited
2005
Optical rotation calculation of a highly flexible molecule: the case of paraconic acid.
The absolute configuration of (S)-(-)-paraconic acid is correctly assigned on the basis of ab initio calculations of the specific… Expand
Highly Cited
2002
Highly Cited
2002
Free-radical-mediated conjugate additions. Enantioselective synthesis of butyrolactone natural products: (-)-enterolactone, (-)-arctigenin, (-)-isoarctigenin, (-)-nephrosteranic acid, and…
Lewis acid-mediated conjugate addition of alkyl radicals to a differentially protected fumarate 10 produced the monoalkylated… Expand
Highly Cited
2002
Highly Cited
2002
Efficient entry to highly functionalized beta-lactams by regio- and stereoselective 1,3-dipolar cycloaddition reaction of 2-azetidinone-tethered nitrones. Synthetic applications.
Racemic as well as optically pure 2-azetidinone-tethered nitrones, both cyclic and acyclic, were smoothly prepared from 4… Expand
1996
1996
Homochiral synthesis of paraconic acid and the biosynthesis of amphotericin B
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