paquinimod

Known as: N,5-Diethyl-4-Hydroxy-1-Methyl-2-Oxo-N-Phenyl-1,2-Dihydroquinoline-3-Carboxamide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2012-2016
012320122016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Pneumococcal meningitis remains a potentially lethal and debilitating disease, mainly due to brain damage from sustained… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2016
2016
BACKGROUND Systemic Sclerosis (SSc) is an autoimmune disease characterized by vascular and immune dysfunction. A hallmark of SSc… (More)
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2016
2016
INTRODUCTION Quinoline-3-carboximide compounds, such as paquinimod, which targets the protein S100A9, have demonstrated efficacy… (More)
Is this relevant?
2016
2016
OBJECTIVE The alarmins S100A8 and S100A9 have been shown to regulate synovial activation, cartilage damage, and osteophyte… (More)
Is this relevant?
2015
2015
OBJECTIVES Alarmins S100A8/A9 regulate pathology in experimental osteoarthritis (OA). Paquinimod is an immunomodulatory compound… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2015
2015
BACKGROUND Neutrophilic inflammation often persists for days despite effective antibiotic treatment and contributes to brain… (More)
Is this relevant?
2015
2015
cell surface marker PSGL-1 (P-selectin glycoprotein ligand 1) to E-selectin on vascular endothelial cells led to the release of… (More)
Is this relevant?
2014
2014
Quinoline-3-carboxamides (Q-compounds) are currently in clinical development for both autoimmune disease and cancer. We have… (More)
Is this relevant?
2013
2013
Quinoline-3-carboxamide compounds (Q compounds) have demonstrated efficacy in treating autoimmune disease in both humans and mice… (More)
Is this relevant?
2012
2012
OBJECTIVE To assess the efficacy of paquinimod, a new immunomodulatory small molecule, in a murine lupus model, and to evaluate… (More)
Is this relevant?