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paquinimod

Known as: N,5-Diethyl-4-Hydroxy-1-Methyl-2-Oxo-N-Phenyl-1,2-Dihydroquinoline-3-Carboxamide 
 
National Institutes of Health

Papers overview

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2018
2018
Quinoline-3-carboxamides (Q substances) are small molecule compounds with anti-inflammatory properties. In this study, we used… Expand
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2018
2018
Quinoline-3-carboxamides (Q compounds) are immunomodulatory compounds that have shown efficacy both in autoimmune disease and… Expand
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2016
2016
BACKGROUND Systemic Sclerosis (SSc) is an autoimmune disease characterized by vascular and immune dysfunction. A hallmark of SSc… Expand
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2015
2015
OBJECTIVES Alarmins S100A8/A9 regulate pathology in experimental osteoarthritis (OA). Paquinimod is an immunomodulatory compound… Expand
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2014
2014
Quinoline-3-carboxamides (Q-compounds) are currently in clinical development for both autoimmune disease and cancer. We have… Expand
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2014
2014
Background Paquinimod (ABR-215757) is an oral small molecule compound that belongs to the quinoline-3-carboxamide derivatives, a… Expand
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2013
2013
Quinoline-3-carboxamide compounds (Q compounds) have demonstrated efficacy in treating autoimmune disease in both humans and mice… Expand
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2013
2013
Background There is increasing evidence that synovial activation contributes to osteoarthritis (OA) pathology and that it is… Expand
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2012
2012
OBJECTIVE To assess the efficacy of paquinimod, a new immunomodulatory small molecule, in a murine lupus model, and to evaluate… Expand
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2012
2012
OBJECTIVE: To assess the efficacy of ABR-215757, a new immunomodulatory small molecule in a murine SLE model, to evaluate the… Expand
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