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pantethine

Known as: D-Bis(N-Pantothenyl-2-Aminoethyl)-Disulfide, bis(N-pantothenylamidoethyl) disulfide 
 
National Institutes of Health

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Broader (1)

Pantetheine
analogs & derivatives

Papers overview

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Highly Cited
2014
Highly Cited
2014
Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model
Pantothenate kinase-associated neurodegeneration, caused by mutations in the PANK2 gene, is an autosomal recessive disorder… Expand
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Highly Cited
2010
Highly Cited
2010
Pantethine rescues a Drosophila model for pantothenate kinase–associated neurodegeneration
Pantothenate kinase–associated neurodegeneration (PKAN), a progressive neurodegenerative disorder, is associated with impairment… Expand
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Highly Cited
2008
Highly Cited
2008
Protection against cerebral malaria by the low-molecular-weight thiol pantethine
We report that administration of the low-molecular-weight thiol pantethine prevented the cerebral syndrome in Plasmodium berghei… Expand
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Review
2001
Review
2001
Natural therapies for ocular disorders, part two: cataracts and glaucoma.
  • K. Head
  • Alternative medicine review : a journal of…
  • 2001
    • Corpus ID: 936933
Pathophysiological mechanisms of cataract formation include deficient glutathione levels contributing to a faulty antioxidant… Expand
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Highly Cited
1998
Highly Cited
1998
Coenzyme A Disulfide Reductase, the Primary Low Molecular Weight Disulfide Reductase from Staphylococcus aureus
The human pathogen Staphylococcus aureus does not utilize the glutathione thiol/disulfide redox system employed by eukaryotes and… Expand
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1996
1996
Delay or inhibition of rat lens opacification using pantethine and WR-77913.
Pantethine and the amino phosphorothioate, WR-77913, protected lenses against increased light scattering and opacification during… Expand
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1988
1988
Modulation of HMG-CoA reductase activity by pantetheine/pantethine.
The ability of pantetheine/pantethine to modulate the activity of HMG-CoA reductase (EC 1.1.1.34) was determined in vitro with… Expand
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1985
1985
Metabolism of pantethine in cystinosis.
D-Pantethine is a conjugate of the vitamin pantothenic acid and the low-molecular-weight aminothiol cysteamine. Pantethine is an… Expand
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1984
1984
Controlled evaluation of pantethine, a natural hypolipidemic compound, in patients with different forms of hyperlipoproteinemia.
Pantethine (P), the stable disulphate form of pantetheine, major component and precursor of coenzyme A, was evaluated within a… Expand
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1970
1970
The enzymatic breakdown of pantethine to pantothenic acid and cystamine.
The enzyme splitting pantethine into pantothenic acid and cystamine has been purified about 3000 times starting from horse kidney… Expand
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