pantethine

Known as: D-Bis(N-Pantothenyl-2-Aminoethyl)-Disulfide, bis(N-pantothenylamidoethyl) disulfide 
 
National Institutes of Health

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Pantetheine
analogs & derivatives

Papers overview

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Highly Cited
2010
Highly Cited
2010
Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration.
Pantothenate kinase-associated neurodegeneration (PKAN), a progressive neurodegenerative disorder, is associated with impairment… (More)
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Review
2009
Review
2009
Current medical aspects of pantethine.
Pantethine, the stable disulfide form of pantetheine, is the major precursor of coenzyme A, which plays a central role in the… (More)
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Highly Cited
2008
Highly Cited
2008
Protection against cerebral malaria by the low-molecular-weight thiol pantethine.
We report that administration of the low-molecular-weight thiol pantethine prevented the cerebral syndrome in Plasmodium berghei… (More)
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Review
1990
Review
1990
Preclinical and clinical studies with cysteamine and pantethine related to the central nervous system
1. Cysteamine is formed by degradation of coenzyme A (CoA) and causes somatostatin (SS), prolactin and noradrenaline depletion in… (More)
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1987
1987
Lowering effect of pantethine on plasma beta-thromboglobulin and lipids in diabetes mellitus.
Pantethine in a dosage of 600 mg for the first 3 months, and in a dosage of 1200 mg for the second 6 months was given to 16… (More)
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1987
1987
Pantethine inhibits cholesterol and fatty acid syntheses and stimulates carbon dioxide formation in isolated rat hepatocytes.
The effects of pantethine on cholesterol and fatty acid metabolism were investigated in isolated rat hepatocytes. Preincubation… (More)
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1986
1986
Lipoprotein changes induced by pantethine in hyperlipoproteinemic patients: adults and children.
Following a brief outline of current knowledge concerning atherosclerosis and its treatment, the authors describe the results… (More)
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1985
1985
Metabolism of pantethine in cystinosis.
D-Pantethine is a conjugate of the vitamin pantothenic acid and the low-molecular-weight aminothiol cysteamine. Pantethine is an… (More)
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1985
1985
Changes in fatty acid composition of the single platelet phospholipids induced by pantethine treatment.
In a single-blind cross-over study the effect of oral treatment with pantethine on plasma and platelet lipid composition was… (More)
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1975
1975
Protective effect of pantethine on experimental thrombocytopenia in the rat.
The effects of pantethine on circulating platelet counts and platelet functions were studied in normal and experimentally… (More)
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