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pamiteplase
Known as:
275-L-Glutamic Acid-(1-91)-(174-527)-Plasminogen Activator (Human Tissue-Type Protein Moiety)
National Institutes of Health
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Related topics
Related topics
3 relations
Broader (2)
Recombinant Proteins
alteplase
Narrower (1)
YM 866
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
THROMBOLYTIC & CYTOTOXIC EFFECT OF DIFFERENT HERBAL EXTRACTS
M. Anwar
,
I. Khan
,
M. Sarkar
,
S. Barua
,
A. M. Kamal
,
M. Hosen
2011
Corpus ID: 18695702
An in-vitro thrombolytic model was used to check the clot lysis effect of four herbal extracts viz., Honey, Nigella sativa…
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Review
2008
Review
2008
Fibrin binding and the regulation of plasminogen activators during thrombolytic therapy.
C. Longstaff
,
S. Williams
,
C. Thelwell
Cardiovascular & hematological agents in…
2008
Corpus ID: 19213124
First generation thrombolytics (streptokinase and urokinase) had no fibrin binding capabilities and caused systemic plasminogen…
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2003
2003
Reduction of infarction volume by bolus injection of pamiteplase, a modified tissue plasminogen activator with a longer half-life
Yasuyuki Suzuki
,
T. Kano
,
Y. Katayama
,
E. Tejima
,
T. Harada
Neurological research
2003
Corpus ID: 36716096
Abstract Using a rat model of thromboembolic stroke we evaluated whether or not fibrinolysis by bolus injection of pamiteplase, a…
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2001
2001
Protective effects of pamiteplase, a modified t-PA, in a rat model of embolic stroke
T. Sumii
,
A. Singhal
,
+4 authors
E. Lo
Neuroreport
2001
Corpus ID: 32873966
The effects of alteplase (tissue plasminogen activator, t-PA) and pamiteplase (a modified t-PA with longer half-life and…
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Review
2000
Review
2000
Third-generation thrombolytic drugs.
M. Verstraete
The American journal of medicine
2000
Corpus ID: 1033227
2000
2000
Determination, pharmacokinetics and protein binding of a novel tissue-type plasminogen activator, pamiteplase in human plasma
K. Oikawa
,
T. Watanabe
,
I. Miyamoto
,
S. Higuchi
Xenobiotica; the fate of foreign compounds in…
2000
Corpus ID: 23995225
1. An enzyme-linked immunosorbent assay (ELISA) and functional bioassay to determine immunoreactive and bioactive concentrations…
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2000
2000
Comparison of drug disposition between wild-type and novel tissue-type plasminogen activator pamiteplase in rats.
K. Oikawa
,
T. Watanabe
,
S. Higuchi
Drug metabolism and disposition: the biological…
2000
Corpus ID: 22761547
The pharmacokinetics of pamiteplase in rats was compared with the pharmacokinetics of recombinant wild-type tissue-type…
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2000
2000
Comparison of receptor-mediated endocytosis kinetics between wild-type t-PA and recombinant pamiteplase in isolated rat hepatocytes and liver cell plasma membranes
K. Oikawa
,
T. Watanabe
,
S. Higuchi
Xenobiotica; the fate of foreign compounds in…
2000
Corpus ID: 46561520
1. Differences in receptor-mediated endocytosis kinetics between pamiteplase, an engineered t-PA, and an unmodified rt-PA were…
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1999
1999
Monosaccharide composition analysis of pamiteplase by anion exchange chromatography with pulsed amperometric detection.
H. Yokota
,
K. Mori
,
H. Yamaguchi
,
H. Kaniwa
,
N. Saisho
Journal of pharmaceutical and biomedical analysis
1999
Corpus ID: 23828493
1997
1997
Single and repeated intravenous toxicity studies of pamiteplase (genetical recombination) in rats and monkeys.
A. Ishikawa
,
T. Ohata
,
+4 authors
S. Okazaki
The Journal of toxicological sciences
1997
Corpus ID: 24810180
Single and repeated intravenous toxicity studies of Pamiteplase (genetical recombination) YM866, a novel recombinant human tissue…
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