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pamiteplase

Known as: 275-L-Glutamic Acid-(1-91)-(174-527)-Plasminogen Activator (Human Tissue-Type Protein Moiety) 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Recombinant Proteinsalteplase

Narrower (1)

YM 866

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
THROMBOLYTIC & CYTOTOXIC EFFECT OF DIFFERENT HERBAL EXTRACTS
An in-vitro thrombolytic model was used to check the clot lysis effect of four herbal extracts viz., Honey, Nigella sativa… 
Review
2008
Review
2008
Fibrin binding and the regulation of plasminogen activators during thrombolytic therapy.
First generation thrombolytics (streptokinase and urokinase) had no fibrin binding capabilities and caused systemic plasminogen… 
2003
2003
Reduction of infarction volume by bolus injection of pamiteplase, a modified tissue plasminogen activator with a longer half-life
Abstract Using a rat model of thromboembolic stroke we evaluated whether or not fibrinolysis by bolus injection of pamiteplase, a… 
2001
2001
Protective effects of pamiteplase, a modified t-PA, in a rat model of embolic stroke
The effects of alteplase (tissue plasminogen activator, t-PA) and pamiteplase (a modified t-PA with longer half-life and… 
Review
2000
Review
2000
Third-generation thrombolytic drugs.
  • M. Verstraete
  • The American journal of medicine
  • 2000
  • Corpus ID: 1033227
2000
2000
Determination, pharmacokinetics and protein binding of a novel tissue-type plasminogen activator, pamiteplase in human plasma
1. An enzyme-linked immunosorbent assay (ELISA) and functional bioassay to determine immunoreactive and bioactive concentrations… 
2000
2000
Comparison of drug disposition between wild-type and novel tissue-type plasminogen activator pamiteplase in rats.
The pharmacokinetics of pamiteplase in rats was compared with the pharmacokinetics of recombinant wild-type tissue-type… 
2000
2000
Comparison of receptor-mediated endocytosis kinetics between wild-type t-PA and recombinant pamiteplase in isolated rat hepatocytes and liver cell plasma membranes
1. Differences in receptor-mediated endocytosis kinetics between pamiteplase, an engineered t-PA, and an unmodified rt-PA were… 
1999
1999
Monosaccharide composition analysis of pamiteplase by anion exchange chromatography with pulsed amperometric detection.
1997
1997
Single and repeated intravenous toxicity studies of pamiteplase (genetical recombination) in rats and monkeys.
Single and repeated intravenous toxicity studies of Pamiteplase (genetical recombination) YM866, a novel recombinant human tissue… 
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