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p21 N-Ras Protein

Known as: Proto-Oncogene Protein p21(c-N-ras), p21(N-ras), N-Ras Protein 
p21 N-RAS protein is encoded by the N-RAS gene. RAS proteins are involved in transmembrane signal transduction as monomeric GTP-binding proteins… 
National Institutes of Health

Related topics

Related topics

9 relations
GTP BindingGTP Binding DomainGuanosine Triphosphate PhosphohydrolasesMAPK Signaling Pathway

Broader (1)

Proto-Oncogene Proteins p21(ras)

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
SP174 Antibody Lacks Specificity for NRAS Q61R and Cross-Reacts With HRAS and KRAS Q61R Mutant Proteins in Malignant Melanoma
HRAS, KRAS, and NRAS, highly homologous proteins, are often mutationally activated in cancer. Usually, mutations cluster in… 
2016
2016
MEK1 is required for the development of NRAS-driven leukemia
The dual-specificity kinases MEK1 and MEK2 act downstream of RAS/RAF to induce ERK activation, which is generally considered… 
2014
2014
Down-Regulation of miR-4500 Promoted Non-Small Cell Lung Cancer Growth
Background: Lung cancer is the lead cause of cancer-related mortality around the world. Non-small cell lung cancer (NSCLC… 
2013
2013
Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes.
2013
2013
Selection for Evi1 activation in myelomonocytic leukemia induced by hyperactive signaling through wild-type NRas
Activation of NRas signaling is frequently found in human myeloid leukemia and can be induced by activating mutations as well as… 
2010
2010
Analyses of 81 Chronic Myelomonocytic Leukemia (CMML) for EZH2, TET2, ASXL1, CBL, KRAS, NRAS, RUNX1, IDH1, IDH2, and NPM1 Revealed Mutations In 86.4% of All Patients with TET2 and EZH2 Being of High…
Abstract 296 Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic malignancy that is characterized by features of… 
2010
2010
Clinical outcome and pathologic features associated with NRAS mutation in cutaneous melanoma.
8500 Background: Mutations in NRAS and BRAF are common in cutaneous melanoma leading to constitutive activation of the MAPK… 
Review
2006
Review
2006
A novel somatic K-Ras mutation in juvenile myelomonocytic leukemia
Juvenile myelomonocytic leukemia (JMML) is an aggressive clonal disorder of hematopoietic precursor cells of early childhood… 
2003
2003
NRAS hypermutability in familial melanoma with CDKN2A mutations--cause and effect?
The frequency of cutaneous melanoma has been increasing worldwide for several decades. Approximately 8%–12% of melanomas occur in… 
1990
1990
Detection of preferential NRAS mutations in human male germ cell tumors by the polymerase chain reaction
We have studied 31 male germ cell tumors (GCTs) for probable mutations in codons 12, 13, and 61 of HRAS, KRAS, and NRAS oncogenes… 
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