oxoguanine glycosylase 1, human

Known as: OGG1, DNA-(Apurinic or Apyrimidinic Site) Lyase, DNA-Apurinic or Apyrimidinic Site Lyase 
N-glycosylase/DNA lyase (345 aa, ~39 kDa) is encoded by the human OGG1 gene. This protein is involved in nucleotide excision repair.
National Institutes of Health

Papers overview

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2014
2014
8-Oxoguanine-DNA glycosylase-1 (OGG1) is the primary enzyme for repairing 7,8-dihydro-8-oxoguanine (8-oxoG) via the DNA base… (More)
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2012
2012
Oxidative damage to DNA is mainly repaired via base excision repair, a pathway that is catalyzed by DNA glycosylases such as 8… (More)
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2011
2011
Background: Oxidative stress-induced DNA damage is repaired by proteins in the base excision pathway. Results: We identified a… (More)
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2007
2007
Human 8-oxoguanine-DNA glycosylase (OGG1) is the main human base excision protein that removes a mutagenic lesion 8-oxoguanine (8… (More)
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2005
2005
Oxoguanine DNA glycosylase (OGG1) initiates the repair of 8-oxoguanine (8-oxoG), a major oxidative DNA base modification that has… (More)
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Highly Cited
2003
Highly Cited
2003
Repair of oxidatively damaged bases in the genome via the base excision repair pathway is initiated with excision of these… (More)
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Highly Cited
2001
Highly Cited
2001
8-Oxoguanine-DNA glycosylase 1 (OGG1), with intrinsic AP lyase activity, is the major enzyme for repairing 7,8-dihydro-8… (More)
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Highly Cited
2001
Highly Cited
2001
Mitochondria are not only the major site for generation of reactive oxygen species, but also one of the main targets of oxidative… (More)
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Highly Cited
2001
Highly Cited
2001
8-oxoguanine DNA glycosylase 1 (OGG1) is a DNA repair enzyme that excises 7,8-dihydro-8-oxoguanine (8oxoG) from DNA. Since 8oxoG… (More)
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Highly Cited
1999
Highly Cited
1999
We identified seven alternatively spliced forms of human 8-oxoguanine DNA glycosylase (OGG1) mRNAs, classified into two types… (More)
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