oxaluric acid
National Institutes of Health
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One of the major biomarkers of oxidative stress and oxidative damage of cellular DNA is 8-oxo-7,8-dihydroguanine (8-oxoGua…
The study of the biological consequences of oxidative damage to DNA requires the characterization of DNA lesions at a molecular…
Oxidative reactions within DNA commonly result in base modifications. Among the four DNA bases, guanine is the most susceptible…
The oxidation of guanine in the dinucleoside monophosphate d(GpT) by an oxo-metalloporphyrin generates a linear oxaluric acid…
The location of carcinogen-modified nucleobases (DNA adducts) within DNA sequences is a critical factor affecting their…
Synthetic oligodeoxynucleotides containing secondary oxidative lesions at guanine nucleobases have been prepared by the site…
8-Oxoguanine (8-oxo-G) is one of the most common DNA lesions present in normal tissues due to exposure to reactive oxygen species…
In a family from which two children suffered from primary hyperoxaluria the renal clearance of (14C) oxalate was studied. The…
Saccharomyces cerevisiae degrades allantoin in five steps to ammonia, CO2, and glyoxylate. Previously we demonstrated that…