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otenzepad

Known as: 11-((2-((diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1-4)benzodiazepine-6-one, 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 11-((2-((diethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro- 
National Institutes of Health

Related topics

Related topics

5 relations

Narrower (1)

AFDX 116

Broader (3)

Anti-Arrhythmia AgentsParasympatholyticsPirenzepine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2001
2001
Prevention of Experimental Autoimmune Cardiomyopathy in Rabbits by Receptor Blockers
We investigated the effects of β1-adrenoceptor blockade and M2-muscarinic receptor antagonist in rabbits which have developed… 
2001
2001
Beneficial Effect of Muscarinic‐2 Antagonist on Dilated Cardiomyopathy Induced by Autoimmune Mechanism against Muscarinic‐2 Receptor
Summary: We have previously shown that a peptide corresponding to the sequence of the second extracellular loop of the human… 
2001
2001
The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria.
1999
1999
Otenzepad. AFDX 116.
  • Drugs in R&D
  • 1999
  • Corpus ID: 7455878
1998
1998
Muscarinic M2 receptor-mediated contraction in the guinea pig Taenia caeci: possible involvement of protein kinase C.
1997
1997
The allosteric interaction of otenzepad at muscarinic acetylcholine M2 receptors in cardiac tissue
1995
1995
Atropine and glycopyrronium show similar binding patterns to M2 (cardiac) and M3 (submandibular gland) muscarinic receptor subtypes in the rat.
Atropine and glycopyrronium are frequently used for premedication to reduce oral and respiratory secretions and prevent… 
1995
1995
Otenzepad shows two populations of binding sites in human gastric smooth muscle.
Cholinergic agonists and antagonists frequently used for gastrointestinal motility disorders often produce adverse effects. A… 
1994
1994
Otenzepad (AF-DX 116) の健康成人男子における安全性および忍容性の検討
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