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Effects of silymarin MZ-80 on oxidative stress in patients with alcoholic cirrhosis. Results of a randomized, double-blind, placebo-controlled clinical study.
BACKGROUND The role of silymarin in the treatment of liver cirrhosis is controversial. AIM Clinical outcome,biochemical profile and the antiperoxidative effects of silymarin MZ-80 during 6 monthsExpand
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Characterization of muscarinic receptor subtypes in human tissues.
The affinities of selective, pirenzepine and AF-DX 116, and classical, N-methylscopolamine and atropine, muscarinic cholinergic receptor antagonists were investigated in displacement bindingExpand
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Antioxidant potential of evening primrose oil administration in hyperlipemic rabbits.
The dietary intake of saturated fatty acids affects arteriosclerosis. We studied the effect of supplementation (15% wt/wt) of a hyperlipemic diet (1.33% cholesterol) with evening primrose oil (EPO)Expand
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Effect of aspirin on prostanoids and nitric oxide production in streptozotocin-diabetic rats with ischemic retinopathy
Abstract. The importance in experimental diabetic retinopathy of prostacyclin and nitric oxide (NO), as well as the possible effect of acetylsalicylic acid (ASA), are well known. To investigate theExpand
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  • Open Access
Drug use for non-hepatic associated conditions in patients with liver cirrhosis
AimsTo study the prescribing patterns of practising physicians for the most frequent non-hepatic associated conditions in patients with liver cirrhosis.MethodsA multi-centre prospective observationalExpand
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  • Open Access
Lipid peroxidation and glutathione system in hyperlipemic rabbits: influence of olive oil administration.
We studied the effect of supplementation (10% w/w) of a hyperlipemic diet (1% cholesterol) with olive oil (OLIV) for 6 weeks in four groups of 10 rabbits each. At the end of this period, weExpand
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  • Open Access
Clonidine decreases intraoperative bleeding in middle ear microsurgery
Background: The antihypertensive drug clonidine is a centrally acting α2 agonist useful as a premedicant because of its sedative, anxiolytic, and analgesic properties. We examined the effect ofExpand
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  • Open Access
Antiplatelet effect of the anaesthetic drug propofol: influence of red blood cells and leucocytes
The present study was designed to investigate the mechanism of the antiplatelet action of the anaesthetic propofol in vitro. Human whole blood was incubated with different concentrations of propofolExpand
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Influence of glucose concentration on the effects of aspirin, ticlopidine and clopidogrel on platelet function and platelet-subendothelium interaction.
Clinical studies have shown that the ability of aspirin to prevent cerebrovascular accidents is weaker in patients with diabetes. The aim of this study was to determine whether high concentrations ofExpand
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  • Open Access
[Generic drugs: good or bad? Physician's knowledge of generic drugs and prescribing habits].
In this article we analyze the responses of 1220 Spanish physicians who participated in a survery about generic drugs. A previously validated questionnaire was sent to physicians through the SpanishExpand
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