osteoblast development

The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Global energy balance in mammals is controlled by the actions of circulating hormones that coordinate fuel production and… (More)
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Highly Cited
2009
Highly Cited
2009
Signaling through the IGF-I receptor by locally synthesized IGF-I or IGF-II is crucial for normal skeletal development and for… (More)
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2008
2008
Loss of function mutations of Perk (eukaryotic translation initiation factor 2 alpha kinase 3) in humans and mice cause severe… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in fibroblast growth factor receptors (Fgfrs) 1-3 cause skeletal disease syndromes in humans. Although these Fgfrs are… (More)
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Highly Cited
2006
Highly Cited
2006
Glucocorticoids (GCs) exert profound effects on bone and are essential for human osteoblast differentiation. However, GCs are… (More)
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Highly Cited
2005
Highly Cited
2005
Signals that govern development of the osteoblast lineage are not well understood. Indian hedgehog (Ihh), a member of the… (More)
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Highly Cited
2005
Highly Cited
2005
Indian hedgehog (Ihh) controls multiple aspects of endochondral skeletal development, including proliferation and maturation of… (More)
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Highly Cited
2004
Highly Cited
2004
The Runt domain transcription factor Runx2 (AML-3, and Cbfa1) is essential for osteoblast development, differentiation, and bone… (More)
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Highly Cited
2004
Highly Cited
2004
Osteoblasts and adipocytes originate from a common progenitor, which arises from bone marrow mesenchymal stroma/stem cells (mMSC… (More)
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Highly Cited
1992
Highly Cited
1992
We examine clonal murine calvarial MC3T3-E1 cells to determine if they exhibit a developmental sequence similar to osteoblasts in… (More)
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