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oroxin B

 
National Institutes of Health

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2 relations

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DisaccharidesFlavones

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2019
2019
Pharmacokinetics and tissue distribution of oroxin B in rats using a validated LC-MS/MS assay.
A highly sensitive LC-MS/MS method was developed to measure oroxin B in rat plasma and tissue homogenates. The analyte and IS… Expand
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2019
2019
Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer
This study aims to investigate the anticancer effect of Oroxin B (OB) both in vitro and in vivo, and the molecular mechanism… Expand
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2018
2018
Evidence for the Involvement of COX-2/VEGF and PTEN/Pl3K/AKT Pathway the Mechanism of Oroxin B Treated Liver Cancer
Background: Oroxin B (OB) is one of flavonoids isolated from traditional Chinese herbal medicine Oroxylum indicum (L.) Vent… Expand
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2016
2016
An LC-MS/MS method for simultaneous determination of four flavonoids from Semen Oroxyli in rat plasma and its application to a pharmacokinetic study.
Semen Oroxyli, a Traditional Chinese Medicine, has many significant pharmacological activities such as analgesic, apoptotic, anti… Expand
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2015
2015
Oroxin B selectively induces tumor-suppressive ER stress and concurrently inhibits tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy.
Cancer cells have both tumor-adaptive and -suppressive endoplasmic reticulum (ER) stress machineries that determine cell fate. In… Expand
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2014
2014
Discovery of xanthine oxidase inhibitors from a complex mixture using an online, restricted-access material coupled with column-switching liquid chromatography with a diode-array detection system
AbstractTo find potential lead compounds for antigout drug discovery, an automated online, restricted-access material coupled… Expand
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2013
2013
Molecular Modeling Reveals the Novel Inhibition Mechanism and Binding Mode of Three Natural Compounds to Staphylococcal α-Hemolysin
α-Hemolysin (α-HL) is a self-assembling, channel-forming toxin that is produced as a soluble monomer by Staphylococcus aureus… Expand
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2013
2013
[Chemical constitunents of seeds of Oroxylum indicum].
OBJECTIVE To study the chemical constituents in the seeds of Oroxylum indicum. METHOD Twenty compounds were isolated and… Expand
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2013
2013
HPLC Determination of Oroxin A and Oroxin B in Oroxylum indicum(L.) Vent
An HPLC method was used for the determination of Oroxin A and Oroxin B in Oroxylum indicum(L.) Vent.A COSMOSIL-C18-MS-Ⅱ(4.6 mm… Expand
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1964
1964
[CHEMICAL STUDIES ON OROXYLEUM INDICUM (L.) VENT. I. TWO NEW FLAVONE GLUCOSIDES OROXIN A AND OROXIN B].
 
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