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BackgroundPreviously, we reported that hepatic transporters were down-regulated consistent with intestinal injury in indomethacin… Expand The effect of orally administered ornoprostil, 17S,20-dimethyl-6-oxoprostaglandin E1 methyl ester, on gastric emptying and on… Expand The study was performed to examine whether indomethacin administered during the initial period of acetic acid-induced gastric… Expand We studied permeability of human small intestine to clarify the following questions. 1) Does indomethacin increase intestinal… Expand A 60-yr-old female patient with rheumatoid arthritis presented with nonsteroidal anti-inflammatory drug (NSAID)-induced ileal… Expand Ornoprostil, a methyl derivative of PGE1 developed in Japan, was tested for its effect on gastric mucosal damage caused by… Expand Prostaglandins (PGs) play important roles in the regulation of various gastric functions. In this study, the effects of various… Expand The effects of TY-10957, a stable PGI2 derivative, on gastroduodenal lesions and secretory responses were examined in rats and… Expand Effects of ethanol and prostaglandin on the glycoprotein synthesis in the gastric mucus cells have been evaluated. The rat… Expand We investigated the roles of endogenous leukotrienes (LTs) and prostaglandins (PGs) in the healing of gastric ulcers induced by… Expand