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oltipraz

Known as: 4-Methyl-5-(pyrazinyl)-3H-1,2-dithiole-3-thione, 3H-1,2-Dithiole-3-thione, 4-methyl-5-pyrazinyl-, 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione 
A synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as… 
National Institutes of Health

Related topics

Related topics

9 relations

Narrower (1)

35 972 R.P.

Broader (6)

Anticarcinogenic AgentsAntiviral AgentsPyrazinesReverse Transcriptase Inhibitors
NCIt Antineoplastic Agent Terminologyoltipraz/vitamin A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Responses to photodynamic therapy in patients with polypoidal choroidal vasculopathy consisting of polyps resembling grape clusters.
2010
2010
Non-innocent bma ligand in a dissymetrically disubstituted diiron dithiolate related to the active site of the [FeFe] hydrogenases.
2006
2006
Therapeutic effects of 10 mg/day rabeprazole administration on reflux esophagitis was not influenced by the CYP2C19 polymorphism
Background:  The acid suppressive effects of omeprazole (OPZ) and lansoprazole (LPZ) are influenced by the CYP2C19 polymorphism… 
2001
2001
In vivo inhibition of human CYP1A2 activity by oltipraz
Abstract. Purpose: Oltipraz is currently undergoing clinical evaluation as a cancer chemopreventive agent, especially with… 
Highly Cited
1998
Highly Cited
1998
Photodynamic therapy of naturally occurring tumors in animals using a novel benzophenothiazine photosensitizer.
5-Ethylamino-9-diethylaminobenzo[a]phenothiazinium chloride (EtNBS) is a novel photodynamic therapy (PDT) photosensitizer with… 
Highly Cited
1995
Highly Cited
1995
Pharmacokinetics and pharmacodynamics of oltipraz as a chemopreventive agent.
Oral oltipraz, as a single-dose treatment, was evaluated as a chemopreventive agent in 31 normal subjects. In a subset of… 
1994
1994
Hydrophobic Zn(II)-naphthalocyanines as photodynamic therapy agents for Lewis lung carcinoma.
1993
1993
Oltipraz, an inhibitor of human immunodeficiency virus type 1 replication.
Glutathione depletion may play a pivotal role in the pathogenesis of human immunodeficiency virus type-1 (HIV-1) infection. Since… 
1989
1989
Factors influencing the induction of DNA single strand breaks in rats by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
1987
1987
PHOTODYNAMIC THERAPY OF A MURINE TUMOR FOLLOWING SENSITISATION WITH CHLORO ALUMINUM SULFONATED PHTHALOCYANINE
Abstract Syngeneic mice bearing a colorectal carcinoma (Colo 26) growing subcutaneously in the flank region received photodynamic… 
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