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olopatadine

Known as: 11-(3-(dimethylamino)propylidene)-6,11-dihydrodibenz(b,e)oxepin-2-acetic acid, Olopatadina, Olopatadin 
A dual action selective histamine H1 receptor antagonist and mast cell stabilizer with anti-allergic activity. Olopatadine stabilizes mast cells and… 
National Institutes of Health

Related topics

Related topics

10 relations
Allergic ConjunctivitisDrug AllergyHistamine H1 Receptor Antagonists [MoA]Olopatadine hydrochloride

Narrower (4)

OpatanolPATANASEPatanolPazeo

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Comparison of Olopatadine and Fluorometholone in Contact Lens-Induced Papillary Conjunctivitis
Purpose: The purpose of this study was to compare the efficacy of olopatadine with fluorometholone in contact lens-induced mild… 
Review
2008
Review
2008
Olopatadine 0.2% ophthalmic solution: the first ophthalmic antiallergy agent with once-daily dosing.
BACKGROUND Olopatadine 0.2% is the first topical ophthalmic antihistamine/mast cell stabilizer indicated for once-daily dosing… 
2008
2008
Effects of Ototopical Antihistamine on Otitis Media in an Allergic Rat
Objectives/Hypothesis: A reliable model of allergy has been created in the Brown Norway rat. In this model, allergen presentation… 
2007
2007
Ocular anti‐allergic compounds selectively inhibit human mast cell cytokines in vitro and conjunctival cell infiltration in vivo
Background Conjunctival mast cells (MCs) are important effector cells in seasonal allergic conjunctivitis, via histamine and… 
2006
2006
Histamine-induced vasodilation and vasoconstriction in the mesenteric resistance artery of the rat.
2006
2006
Improved quality of life among seasonal allergic rhinitis patients treated with olopatadine HCl nasal spray 0.4% and olopatadine HCl nasal spray 0.6% compared with vehicle placebo.
Seasonal allergic rhinitis (SAR) exerts a significant adverse impact on health-related quality of life (QoL) and productivity of… 
2004
2004
Preclinical and clinical antiallergic effect of olopatadine 0.2% solution 24 hours after topical ocular administration.
Pharmacologic studies examined the potential of a solution containing olopatadine to maintain and extend antiallergic efficacy… 
2004
2004
The promotion of eosinophil degranulation and adhesion to conjunctival epithelial cells by IgE-activated conjunctival mast cells.
2002
2002
Effects of olopatadine, a new antiallergic agent, on human liver microsomal cytochrome P450 activities.
Olopatadine, a new histamine H(1) receptor-selective antagonist, is a tricyclic drug containing an alkylamino moiety. Some… 
2000
2000
Olopatadine inhibits TNFalpha release from human conjunctival mast cells.
BACKGROUND Tumor necrosis factor-alpha (TNFalpha) release likely plays a crucial role in allergic ocular inflammation via… 
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