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In the context of drug discovery, novel spirocyclic pyrrolidines have been synthesized in two steps from common three- to seven… Expand This study described distribution characteristics of olamufloxacin (HSR-903) in lung epithelial lining fluid (ELF) and alveolar… Expand Background: The in vitro antimicrobial activities of new fluoroquinolones were tested against quinolone-resistant Haemophilus… Expand This study was performed to characterize the protonation equilibrium at the molecular level and pH-dependent lipophilicity of… Expand OBJECTIVES
To determine the susceptibility of southern African strains of Yersinia pestis to novel as well as conventional… Expand The activity of the fluoroquinolone olamufloxacin (HSR-903) against Legionella spp. was studied in vitro and in vivo. The… Expand The in vivo activity of olamufloxacin (HSR-903), a new fluoroquinolone, was evaluated and compared with ciprofloxacin… Expand Hokuriku is developing olamufloxacin, a quinolone antibiotic that inhibits DNA gyrase, for the potential treatment of various… Expand