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nucleophosmin

Known as: B23 Nuclear Matrix Protein, NPM1, nucleophosmid 
Nucleophosmin (294 aa, ~33 kDa) is encoded by the human NPM1 gene. This protein is involved in ribosomal function.
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
BACKGROUND Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The… 
Highly Cited
2009
Highly Cited
2009
BACKGROUND The full complement of DNA mutations that are responsible for the pathogenesis of acute myeloid leukemia (AML) is not… 
Review
2007
Review
2007
The nucleophosmin (NPM1) gene encodes for a multifunctional nucleocytoplasmic shuttling protein that is localized mainly in the… 
Review
2006
Review
2006
NPM1 is a crucial gene to consider in the context of the genetics and biology of cancer. NPM1 is frequently overexpressed… 
Highly Cited
2005
Highly Cited
2005
BACKGROUND Nucleophosmin (NPM), a nucleocytoplasmic shuttling protein with prominent nucleolar localization, regulates the ARF… 
Highly Cited
2005
Highly Cited
2005
Nucleophosmin (NPM1) exon-12 gene mutations are the hallmark of a large acute myelogenous leukemia (AML) subgroup with normal… 
Highly Cited
2005
Highly Cited
2005
Nucleophosmin (also known as NPM, B23, NO38) is a nucleolar protein directly implicated in cancer pathogenesis, as the NPM1 gene… 
Highly Cited
2005
Highly Cited
2005
To assess the prognostic relevance of mutations in the NPM1 gene encoding a nucleocytoplasmic shuttle protein in younger adults… 
Highly Cited
2005
Highly Cited
2005
Mutations in nucleophosmin NPM1 are the most frequent acquired molecular abnormalities in acute myeloid leukemia (AML). We… 
Highly Cited
2002
Highly Cited
2002
Nucleophosmin (NPM) is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and…