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nucleophosmin

Known as: B23 Nuclear Matrix Protein, NPM1, nucleophosmid 
Nucleophosmin (294 aa, ~33 kDa) is encoded by the human NPM1 gene. This protein is involved in ribosomal function.
National Institutes of Health

Related topics

Related topics

10 relations
Cell NucleolusLiver carcinomaNPM1 geneNPM1 wt Allele

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NPM1 protein, humanNpm1 protein, mouse

Papers overview

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Highly Cited
2006
Highly Cited
2006
Polyamine Depletion Increases Cytoplasmic Levels of RNA-binding Protein HuR Leading to Stabilization of Nucleophosmin and p53 mRNAs*
Polyamines are essential for maintaining normal intestinal epithelial integrity, an effect that relies, at least in part, on… 
Highly Cited
2004
Highly Cited
2004
B23/Nucleophosmin Serine 4 Phosphorylation Mediates Mitotic Functions of Polo-like Kinase 1*
Phosphoprotein profiling by Kinetworks™ analysis of M-phase-arrested HeLa cells by nocodazole treatment revealed that a novel… 
Highly Cited
2003
Highly Cited
2003
Nucleophosmin-anaplastic lymphoma kinase of anaplastic large-cell lymphoma recruits, activates, and uses pp60c-src to mediate its mitogenicity.
Anaplastic large-cell lymphomas (ALCLs) are lymphomas of T or null phenotype often associated with a chromosomal translocation, t… 
Highly Cited
2001
Highly Cited
2001
The Nucleolar Phosphoprotein B23 Interacts with Hepatitis Delta Antigens and Modulates the Hepatitis Delta Virus RNA Replication*
Hepatitis delta virus (HDV) encodes two isoforms of delta antigens (HDAgs). The small form of HDAg is required for HDV RNA… 
Highly Cited
1998
Highly Cited
1998
Nucleolar localization of the nucleophosmin-anaplastic lymphoma kinase is not required for malignant transformation.
The (2;5)(p23;q35) lymphoma-associated chromosomal translocation creates a novel fusion gene that incorporates parts of the… 
Highly Cited
1996
Highly Cited
1996
Sedimentation analyses of the salt- and divalent metal ion-induced oligomerization of nucleolar protein B23.
Protein B23 is a major nonribosomal nucleolar protein and putative ribosome assembly factor that has been demonstrated to form… 
Highly Cited
1995
Highly Cited
1995
Interaction of nucleolar protein B23 with peptides related to nuclear localization signals.
Nucleolar protein B23 is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization… 
Highly Cited
1993
Highly Cited
1993
Expression and subcellular locations of two forms of nucleolar protein B23 in rat tissues and cells.
Protein B23 (Mr/pI = 38,000/5.1) is a major RNA-associated nucleolar phosphoprotein and putative ribosome assembly factor… 
Highly Cited
1988
Highly Cited
1988
Identification of numatrin, the nuclear matrix protein associated with induction of mitogenesis, as the nucleolar protein B23. Implication for the role of the nucleolus in early transduction of…
Highly Cited
1987
Highly Cited
1987
"Numatrin," a nuclear matrix protein associated with induction of proliferation in B lymphocytes.
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