Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 205,985,317 papers from all fields of science
Search
Sign In
Create Free Account
nucleophosmin
Known as:
B23 Nuclear Matrix Protein
, NPM1
, nucleophosmid
Expand
Nucleophosmin (294 aa, ~33 kDa) is encoded by the human NPM1 gene. This protein is involved in ribosomal function.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
10 relations
Cell Nucleolus
Liver carcinoma
NPM1 gene
NPM1 wt Allele
Expand
Narrower (2)
NPM1 protein, human
Npm1 protein, mouse
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
Jay P. Patel
,
M. Gönen
,
+28 authors
R. Levine
The New England journal of medicine
2012
Corpus ID: 2600699
BACKGROUND Acute myeloid leukemia (AML) is a heterogeneous disease with respect to presentation and clinical outcome. The…
Expand
Highly Cited
2009
Highly Cited
2009
Recurring mutations found by sequencing an acute myeloid leukemia genome.
E. Mardis
,
L. Ding
,
+55 authors
T. Ley
The New England journal of medicine
2009
Corpus ID: 25183214
BACKGROUND The full complement of DNA mutations that are responsible for the pathogenesis of acute myeloid leukemia (AML) is not…
Expand
Review
2007
Review
2007
Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): biologic and clinical features.
B. Falini
,
I. Nicoletti
,
M. Martelli
,
C. Mecucci
Blood
2007
Corpus ID: 18303068
The nucleophosmin (NPM1) gene encodes for a multifunctional nucleocytoplasmic shuttling protein that is localized mainly in the…
Expand
Review
2006
Review
2006
Nucleophosmin and cancer
S. Grisendi
,
C. Mecucci
,
B. Falini
,
P. Pandolfi
Nature Reviews Cancer
2006
Corpus ID: 7461933
NPM1 is a crucial gene to consider in the context of the genetics and biology of cancer. NPM1 is frequently overexpressed…
Expand
Highly Cited
2005
Highly Cited
2005
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.
B. Falini
,
C. Mecucci
,
+20 authors
M. Martelli
The New England journal of medicine
2005
Corpus ID: 30141056
BACKGROUND Nucleophosmin (NPM), a nucleocytoplasmic shuttling protein with prominent nucleolar localization, regulates the ARF…
Expand
Highly Cited
2005
Highly Cited
2005
Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype.
S. Schnittger
,
C. Schoch
,
+6 authors
B. Falini
Blood
2005
Corpus ID: 978635
Nucleophosmin (NPM1) exon-12 gene mutations are the hallmark of a large acute myelogenous leukemia (AML) subgroup with normal…
Expand
Highly Cited
2005
Highly Cited
2005
Role of nucleophosmin in embryonic development and tumorigenesis
S. Grisendi
,
R. Bernardi
,
+4 authors
P. Pandolfi
Nature
2005
Corpus ID: 7908598
Nucleophosmin (also known as NPM, B23, NO38) is a nucleolar protein directly implicated in cancer pathogenesis, as the NPM1 gene…
Expand
Highly Cited
2005
Highly Cited
2005
Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations.
K. Döhner
,
R. Schlenk
,
+6 authors
H. Döhner
Blood
2005
Corpus ID: 2786429
To assess the prognostic relevance of mutations in the NPM1 gene encoding a nucleocytoplasmic shuttle protein in younger adults…
Expand
Highly Cited
2005
Highly Cited
2005
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic…
R. Verhaak
,
C. Goudswaard
,
+8 authors
P. Valk
Blood
2005
Corpus ID: 25061107
Mutations in nucleophosmin NPM1 are the most frequent acquired molecular abnormalities in acute myeloid leukemia (AML). We…
Expand
Highly Cited
2002
Highly Cited
2002
Nucleophosmin regulates the stability and transcriptional activity of p53
E. Colombo
,
J. Marine
,
Davide Danovi
,
B. Falini
,
P. Pelicci
Nature Cell Biology
2002
Corpus ID: 24923289
Nucleophosmin (NPM) is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
,
Terms of Service
, and
Dataset License
ACCEPT & CONTINUE