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nucleic acid biosynthesis

 
National Institutes of Health

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2018
2018
Polymerases (Pols) synthesize the double-stranded nucleic acids in the Watson-Crick (W-C) conformation, which is critical for DNA… Expand
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2004
2004
Type IB topoisomerases are enzymes essential for the orderly synthesis of nucleic acids and are the molecular target for… Expand
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2004
2004
ABSTRACT Distamycin A has been described as an inhibitor of the cellular pathogenesis of vaccinia virus in culture. Distamycin is… Expand
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2004
2004
MOTIVATION Hybridization of oligonucleotides with longer nucleotide sequences is an essential step in nucleic acid biosynthesis… Expand
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2003
2003
Oxidized low density lipoproteins (OxLDL) play a key role in atherogenesis and induce a wide range of biological effects on… Expand
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Highly Cited
2000
Highly Cited
2000
Cantharidin is isolated from Mylabris phalerata Pallas and is a potent inhibitor of hepatocellular carcinoma cells (Hep 3B cells… Expand
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1983
1983
Cyanocycline A was cytotoxic against Meth A cells in vitro, and also showed marked activity against the same cell line grown as… Expand
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Highly Cited
1959
Highly Cited
1959
We have previously reported on the tumor inhibitory properties of 5-fluorouracil and 5-fluoroorotic acid (3, 4), prepared by… Expand
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Highly Cited
1958
Highly Cited
1958
Summary 1.The effects of 5-fluorouracil and 5-fluoroorotic acid on nucleic acid biosynthesis in livers, spleens, and Ehrlich… Expand
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1951
1951
As a result of the investigations of Kidder and coworkers, it has recently become possible to grow the ciliated prot.oaoan… Expand
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