northiaden

BACKGROUND This study looks at the outcome of infants exposed to dothiepin in breast milk in an attempt to guide clinicians on… Expand

Plasma and breast‐milk concentrations of dothiepin and its metabolite northiaden were measured in 20 lactating women receiving… Expand

Dosulepin, 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenzo [b,e]thiepin hydrochloride, is a thio analogue of amitriptyline… Expand

A comparative study of the ability to block the amine pump was carried out on tricyclic antidepressants including dothiepin and… Expand

SummaryThe pharmacokinetics of dothiepin were evaluated in 9 depressed patients following a single oral dose of 75mg. Blood and… Expand

The affinities of dothiepin and its principal metabolites northiaden, dothiepin sulphoxide and northiaden sulphoxide for [3H… Expand

1 Seven healthy volunteers received a single oral dose of 75 mg dothiepin. Plasma concentrations of dothiepin were measured by… Expand

In a double-blind parallel group study, thirty-two patients suffering from a primary affective disorder received either dothiepin… Expand

Five healthy volunteers took part in a crossover study which examined the serum concentrations of dothiepin and northiaden after… Expand

A method has been developed for the separation and measurement of dothiepin and the N-desmethyl metabolite, northiaden, in human… Expand