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noroxymorphone

Known as: 14-Hydroxydihydronormorphinone, 7,8-Dihydro-14-Hydroxynormorphinone, Morphinan-6-One, 4,5-Epoxy-3,14-Dihydroxy-, (5Alpha)- 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Background and purpose:  There is high interindividual variability in the activity of drug‐metabolizing enzymes catalysing the… Expand
2009
2009
A simple isocratic reversed-phase high-performance liquid chromatographic method (RP-HPLC) was developed for the simultaneous… Expand
2009
2009
A highly sensitive method was developed to measure naloxone and its metabolite nornaloxone in human plasma, urine, and human… Expand
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Highly Cited
2009
Highly Cited
2009
Background:Oxycodone is a &mgr;-opioid receptor agonist that is metabolized mainly in the liver by cytochrome P450 3A and 2D6… Expand
2008
2008
A sensitive and specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the… Expand
2008
2008
BACKGROUND:Noroxymorphone is one of the major metabolites of oxycodone. Although oxycodone is commonly used in the treatment of… Expand
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Highly Cited
2006
Highly Cited
2006
In vitro experiments suggest that circulating metabolites of oxycodone are opioid receptor agonists. Clinical and animal studies… Expand
1987
1987
After a 4 mg kg−1 bolus intravenous dose of [15,16‐3H]naltrexonium methiodide to the rat, brain to plasma concentration ratios of… Expand
Highly Cited
1975
Highly Cited
1975
Understanding of the pharmacology of the narcotic antagonist naloxone has been limited by the lack of a convenient and sensitive… Expand
1971
1971
Naloxone, 7,8-dihydro-14-hydroxynormorphinone, and N-allyl-7,8-dihydro-14-hydroxynormorphine have been idenfied in a human urine… Expand