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norlevorphanol

Known as: 3-hydroxymorphinan 
National Institutes of Health

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Broader (1)

Dextromethorphan
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Neuropsychotoxic and neuroprotective potentials of dextromethorphan and its analogs.
Dextromethorphan (3-methoxy-17-methylmorphinan) has complex pharmacologic effects on the central nervous system. Although some of… 
2011
2011
Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple…
2009
2009
A validated SIM GC/MS method for the simultaneous determination of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in biological matrices and its…
Dextromethorphan is used as a probe drug for assessing CYP2D6 and CYP3A4 activity in vivo and in vitro. A SIM GC/MS method… 
2009
2009
Metabolism of dextrorphan by CYP2D6 in different recombinantly expressed systems and its implications for the in vitro assessment of dextromethorphan metabolism.
Cytochrome P450 2D6 (CYP2D6) mediated formation of dextrorphan (DOR) from dextromethorphan (DEX) is widely used as a marker to… 
2009
2009
Inhibitory effect of glutamate release from rat cerebrocortical synaptosomes by dextromethorphan and its metabolite 3-hydroxymorphinan
Review
2008
Review
2008
Neuropsychotoxicity of abused drugs: potential of dextromethorphan and novel neuroprotective analogs of dextromethorphan with improved safety profiles in terms of abuse and neuroprotective effects.
Drug abuse involving dextromethorphan, an antitussive, has been a social problem in various geographic locations since the 1960s… 
2005
2005
Effect of methamphetamine on the pharmacokinetics of dextromethorphan and midazolam in rats
SummaryMethamphetamine is the fourth most frequently reported compound associated with drug abuse on admission of patients to… 
2003
2003
New morphinan derivatives with negligible psychotropic effects attenuate convulsions induced by maximal electroshock in mice.
2002
2002
A sensitive LC-MS/MS assay for the determination of dextromethorphan and metabolites in human urine--application for drug interaction studies assessing potential CYP3A and CYP2D6 inhibition.
1994
1994
Screening for hydroxylation and acetylation polymorphisms in man via simultaneous analysis of urinary metabolites of mephenytoin, dextromethorphan and caffeine by capillary electrophoretic procedures…
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