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nociceptin

Known as: N-OFQ peptide, nociceptin-orphanin FQ, orphanin FQ 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

Nociceptin, human

Broader (2)

Opioid PeptideVasodilator Agents
PNOC gene

Papers overview

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2002
2002
The orphanin receptor agonist RO 64-6198 does not induce place conditioning in rats
The abuse liability of Ro 64-6198, an orphanin FQ (OFQ) receptor full agonist that exhibits anxiolytic properties, was evaluated… 
Highly Cited
2001
Highly Cited
2001
Cutting Edge: Nociceptin Stimulates Neutrophil Chemotaxis and Recruitment: Inhibition by Aspirin-Triggered-15-Epi-Lipoxin A41
The nociceptin receptor (Noci-R) is a G protein-coupled receptor present in neural tissues and its activation by nociceptin is… 
Highly Cited
2001
Highly Cited
2001
Actions of nociceptin/orphanin FQ and other prepronociceptin products on rat rostral ventromedial medulla neurons in vitro
1 Whole‐cell patch clamp recordings were made from rat rostral ventromedial medulla (RVM) neurons in vitro to investigate the… 
2001
2001
Effects of Ro 64-6198 in nociceptin/orphanin FQ-sensitive isolated tissues
Abstract. The pharmacological profile of the non-peptide OP4 receptor (ORL1, LC132) agonist, Ro 64-6198, was investigated, in… 
2000
2000
Orphanin FQ, but not dynorphin A, accelerates colonic transit in rats.
BACKGROUND & AIMS The endogenous opiate receptor-like 1 ligand, orphanin FQ (OFQ), which structurally resembles dynorphin A, has… 
Highly Cited
1999
Highly Cited
1999
Functional significance of a newly discovered neuropeptide, orphanin FQ, in rat gastrointestinal motility.
Highly Cited
1999
Highly Cited
1999
8-acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as orphanin FQ receptor agonists.
1999
1999
Nociceptin augments K(+) currents in hippocampal CA1 neurons by both ORL-1 and opiate receptor mechanisms.
We previously reported (see also the accompanying paper) that dynorphin A significantly enhanced the voltage-dependent K(+) M… 
Highly Cited
1998
Highly Cited
1998
Nociceptin inhibits non‐adrenergic non‐cholinergic contraction in guinea‐pig airway
1 Electrical field stimulation (EFS) of guinea‐pig isolated main bronchi induced a non‐adrenergic non‐cholinergic (NANC… 
Highly Cited
1996
Highly Cited
1996
Depression of glutamatergic transmission by nociceptin in the neonatal rat hemisected spinal cord preparation in vitro
The present study explored the action of nociceptin, the putative endogenous ligand for the orphan opioid receptor (ORL1), on the… 
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