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PNOC gene

Known as: NOCISTATIN, PPNOC, NOP 
This gene is involved in the modulation of both pain and locomotion.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Significance A potent opioid analgesic without addictive and respiratory adverse effects has been a predominant goal for opioid… Expand
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Review
2007
Review
2007
The advance of functional genomics revealed the superfamily of G-protein coupled receptors (GPCRs). Hundreds of GPCRs have been… Expand
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Highly Cited
2005
Highly Cited
2005
We explored the use of multidimensional scaling (MDS) of tree-to-tree pairwise distances to visualize the relationships among… Expand
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Highly Cited
2003
Highly Cited
2003
The neuropeptide nociceptin, also called orphanin FQ (N/OFQ), is the endogenous agonist of the N/OFQ peptide receptor (NOP… Expand
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Review
2001
Review
2001
While acute pain has a fundamental role to operate a protective system, chronic pain associated with inflammation and nerve… Expand
Review
2000
Review
2000
Nociceptin (NC), alias Orphanin FQ, has been recently identified as the endogenous ligand of the opioid receptor‐like 1 receptor… Expand
Highly Cited
2000
Highly Cited
2000
Nociceptin/orphanin FQ (N/OFQ) and nocistatin (NST) are two recently identified neuropeptides with opposing effects on several… Expand
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Highly Cited
1998
Highly Cited
1998
Prolonged tissue damage or injury often leads to chronic pain states such that noxious stimuli evoke hyperalgesia and innocuous… Expand
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Highly Cited
1997
Highly Cited
1997
In the G‐protein‐coupled receptor superfamily, the opioid receptor subfamily is constituted of the three distinct opioid… Expand
Highly Cited
1996
Highly Cited
1996
Nociceptin (orphanin FQ), the newly discovered natural agonist of opioid receptor-like (ORL1) receptor, is a neuropeptide that is… Expand