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PNOC gene

Known as: NOCISTATIN, PPNOC, NOP 
This gene is involved in the modulation of both pain and locomotion.
National Institutes of Health

Related topics

Related topics

6 relations
Nociceptin, humanNociceptionPrepronociceptin, humanSynaptic Transmission

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
NIR-Responsive Polypeptide Nanocomposite Generates NO Gas, Mild Photothermia and Chemotherapy to Reverse Multidrug Resistant Cancer.
Multidrug resistance (MDR) of cancers that results from overexpression of P-glycoprotein (P-gp) transporter mainly causes… 
Review
2007
Review
2007
Nociceptin/orphanin FQ peptide receptors: pharmacology and clinical implications.
The advance of functional genomics revealed the superfamily of G-protein coupled receptors (GPCRs). Hundreds of GPCRs have been… 
Highly Cited
2005
Highly Cited
2005
Analysis and visualization of tree space.
We explored the use of multidimensional scaling (MDS) of tree-to-tree pairwise distances to visualize the relationships among… 
Highly Cited
2003
Highly Cited
2003
Nociceptin/Orphanin FQ and Its Receptor—Potential Targets for Pain Therapy?
The neuropeptide nociceptin, also called orphanin FQ (N/OFQ), is the endogenous agonist of the N/OFQ peptide receptor (NOP… 
Review
2001
Review
2001
Central and peripheral roles of prostaglandins in pain and their interactions with novel neuropeptides nociceptin and nocistatin
Review
2000
Review
2000
Pharmacology of nociceptin and its receptor: a novel therapeutic target
Nociceptin (NC), alias Orphanin FQ, has been recently identified as the endogenous ligand of the opioid receptor‐like 1 receptor… 
Highly Cited
2000
Highly Cited
2000
Selective Suppression of Inhibitory Synaptic Transmission by Nocistatin in the Rat Spinal Cord Dorsal Horn
Nociceptin/orphanin FQ (N/OFQ) and nocistatin (NST) are two recently identified neuropeptides with opposing effects on several… 
Highly Cited
1998
Highly Cited
1998
Nocistatin, a peptide that blocks nociceptin action in pain transmission
Prolonged tissue damage or injury often leads to chronic pain states such that noxious stimuli evoke hyperalgesia and innocuous… 
Highly Cited
1997
Highly Cited
1997
Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor
In the G‐protein‐coupled receptor superfamily, the opioid receptor subfamily is constituted of the three distinct opioid… 
Highly Cited
1996
Highly Cited
1996
Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene.
Nociceptin (orphanin FQ), the newly discovered natural agonist of opioid receptor-like (ORL1) receptor, is a neuropeptide that is… 
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