nocardicin A
National Institutes of Health
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An LD-carboxypeptidase releasing the terminal D-Ala from UDP-MurNAc-L-Ala-D-Glu-m-A2pm-D-Ala (UDP-MurNAc-tetrapeptide) was…
The catalytic effect of various buffer systems (citrates, acetates, phosphates, borates and carbonates) on the degradation of…
Nocardicin A is the antibiotic which was first found to possess a monocyclic beta-lactam ring. This antibiotic was inactivated by…
The phosphonopeptide L- norvalyl -L-1- aminoethylphosphonic acid [ Nva -Ala(P)] has been studied in combination with 12 beta…
Pseudomonas aeruginosa and Escherichia coli were exposed to nocardicin A, and were subsequently observed with transmission and…
The inhibition of elongation of Bacillus megaterium KM growing in the presence of low concentrations of nocardicin A resulted in…
This study deals with the interaction of nocardicin A with Escherichia coli penicillin-binding proteins. Competition experiments…
We report here a total synthesis of nocardicin A. The antibiotic was obtained as a mixture of diastereoisomers that possessed…