nocardicin
National Institutes of Health
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Cephem and nocardicin-type monocyclic ,8-lactam antibiotics with a formylamino substituent were highly resistant to hydrolysis by…
The biosynthetic gene cluster for the nocardicin A producer Nocardia uniformis subsp. tsuyamanensis ATCC 21806 was recently…
Reaction of the imines 1 and ethyl isobutyrate in the presence of LDA yields β-lactams 2, whereas thioimidate 4 with the same…
Two temperature-sensitive autolysis-defective mutants of Escherichia coli were isolated and shown to be resistant to lysis…
A nocardicin derivative was prepared from penicillin G, confirming that nocardicins have the same configuration as penicillins at…
Synthese et etude biologique de l'acide α-[dichloro-2',6' phenyl-3 methyl-5 isoxazoline-2yl-5] oxo-2 phenylacetamido-3…
New monocyclic beta-lactam antibiotics, formadicins A, B, C and D, were isolated from the culture filtrate of Flexibacter…
Cephem and nocardicin-type monocyclic beta-lactam antibiotics with a formylamino substituent were highly resistant to hydrolysis…
Chlorocardicin is a new monocyclic beta-lactam produced by a Streptomyces sp. It is structurally related to nocardicin A but…
Nocardicin A, a monocyclic beta-lactam antibiotic with modest anti-pseudomonal activity in vitro, controlled an otherwise fatal…