niravoline

A kappa-opioid receptor agonist with edema relieving activity. Niravoline inhibits the scretion of the antiduretic hormone vasopressin thereby… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2000
02419962000

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
BACKGROUND/AIMS In patients with cirrhosis, decreased renal water excretion is a common complication. Niravoline (RU51599), a… (More)
Is this relevant?
2000
2000
To ascertain the effects of niravoline (RU 51599, a selective kappa-opioid receptor agonist) on elevated intracranial pressure… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • table 2
Is this relevant?
2000
2000
Water retention in experimental cirrhosis can be reversed by blocking V(2)-vasopressin (AVP) receptors with the nonpeptide… (More)
  • table 1
  • figure 1
  • figure 3
  • table 2
  • figure 4
Is this relevant?
1999
1999
kappa-Opioid receptor agonists (niravoline) or nonpeptide antidiuretic hormone (ADH) V2 receptor antagonists (OPC-31260) possess… (More)
Is this relevant?
1999
1999
k-Opioid receptor agonists (niravoline) or nonpeptide antidiuretic hormone (ADH) V2 receptor antagonists (OPC-31260) possess… (More)
  • table 1
  • figure 1
  • table 2
  • figure 3
  • figure 2
Is this relevant?
1998
1998
It has recently been reported that kappa-opioid receptor agonists inhibit antidiuretic hormone secretion and promote water… (More)
Is this relevant?
1997
1997
The effect of niravoline (RU 51599), a kappa opioid receptor agonist with water diuretic properties, was assessed on the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
1997
1997
Despite the recent introduction of a number of new compounds, there has of late been a cooling of interest by pharmaceutical… (More)
Is this relevant?
1996
1996
We noninvasively investigated the effects of a single 30-min i.v. infusion of a 2-mg dose of niravoline, a new selective kappa… (More)
Is this relevant?
1996
1996
Because renal water retention is a complication of cirrhosis, niravoline (RU 51,599), a novel kappa (kappa) opioid receptor… (More)
Is this relevant?