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niravoline

A kappa-opioid receptor agonist with edema relieving activity. Niravoline inhibits the scretion of the antiduretic hormone vasopressin thereby… Expand
National Institutes of Health

Papers overview

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2000
2000
Abstract Background/Aims : In patients with cirrhosis, decreased renal water excretion is a common complication. Niravoline… Expand
2000
2000
BACKGROUND/AIMS In patients with cirrhosis, decreased renal water excretion is a common complication. Niravoline (RU51599), a… Expand
2000
2000
Water retention in experimental cirrhosis can be reversed by blocking V(2)-vasopressin (AVP) receptors with the nonpeptide… Expand
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1999
1999
kappa-Opioid receptor agonists (niravoline) or nonpeptide antidiuretic hormone (ADH) V2 receptor antagonists (OPC-31260) possess… Expand
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1998
1998
ABSTRACT It has recently been reported that kappa–opioid receptor agonists inhibit antidiuretic hormone secretion and promote… Expand
1998
1998
It has recently been reported that kappa-opioid receptor agonists inhibit antidiuretic hormone secretion and promote water… Expand
1997
1997
The effect of niravoline (RU 51599), a kappa opioid receptor agonist with water diuretic properties, was assessed on the… Expand
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Highly Cited
1997
Highly Cited
1997
Despite the recent introduction of a number of new compounds, there has of late been a cooling of interest by pharmaceutical… Expand
1996
1996
We noninvasively investigated the effects of a single 30-min i.v. infusion of a 2-mg dose of niravoline, a new selective kappa… Expand
1996
1996
Because renal water retention is a complication of cirrhosis, niravoline (RU 51,599), a novel kappa (κ) opioid receptor agonist… Expand