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niravoline
A kappa-opioid receptor agonist with edema relieving activity. Niravoline inhibits the scretion of the antiduretic hormone vasopressin thereby…
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National Institutes of Health
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Related topics
3 relations
Broader (2)
Benzeneacetamides
Pyrrolidines
Narrower (1)
RU 51599
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Aquaretic effects of niravoline, a kappa-opioid agonist, in patients with cirrhosis.
A. Gadano
,
R. Moreau
,
+5 authors
D. Lebrec
Journal of Hepatology
2000
Corpus ID: 34210904
BACKGROUND/AIMS In patients with cirrhosis, decreased renal water excretion is a common complication. Niravoline (RU51599), a…
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2000
2000
Long-term aquaretic efficacy of a selective nonpeptide V(2)-vasopressin receptor antagonist, SR121463, in cirrhotic rats.
Wladimiro Jiménez
,
C. S. Gal
,
+8 authors
J. Rodés
Journal of Pharmacology and Experimental…
2000
Corpus ID: 2305541
Water retention in experimental cirrhosis can be reversed by blocking V(2)-vasopressin (AVP) receptors with the nonpeptide…
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2000
2000
Aquaretic effects of niravoline, a κ-opioid agonist, in patients with cirrhosis
A. Gadano
,
R. Moreau
,
+5 authors
D. Lebrec
2000
Corpus ID: 73404255
1999
1999
Comparison of two aquaretic drugs (niravoline and OPC-31260) in cirrhotic rats with ascites and water retention.
M. Bosch-Marce
,
J. Poo
,
+8 authors
J. Rodés
Journal of Pharmacology and Experimental…
1999
Corpus ID: 8897842
kappa-Opioid receptor agonists (niravoline) or nonpeptide antidiuretic hormone (ADH) V2 receptor antagonists (OPC-31260) possess…
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1998
1998
Effects of niravoline (RU 51599), a selective kappa-opioid receptor agonist on intracranial pressure in gradually expanding extradural mass lesion.
I. Bemana
,
S. Nagao
Journal of Neurotrauma
1998
Corpus ID: 20895313
It has recently been reported that kappa-opioid receptor agonists inhibit antidiuretic hormone secretion and promote water…
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1997
1997
The kappa opioid agonist niravoline decreases brain edema in the mouse middle cerebral artery occlusion model of stroke.
C. Guéniau
,
C. Oberlander
Journal of Pharmacology and Experimental…
1997
Corpus ID: 1635016
The effect of niravoline (RU 51599), a kappa opioid receptor agonist with water diuretic properties, was assessed on the…
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Highly Cited
1997
Highly Cited
1997
Novel developments with selective, non-peptidic kappa-opioid receptor agonists.
A. Barber
,
R. Gottschlich
Expert Opinion on Investigational Drugs
1997
Corpus ID: 1131679
Despite the recent introduction of a number of new compounds, there has of late been a cooling of interest by pharmaceutical…
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1996
1996
Systemic and regional hemodynamic and biological effects of a new kappa-opioid agonist, niravoline, in healthy volunteers.
É. Bellissant
,
T. Denolle
,
+5 authors
H. Allain
Journal of Pharmacology and Experimental…
1996
Corpus ID: 20568740
We noninvasively investigated the effects of a single 30-min i.v. infusion of a 2-mg dose of niravoline, a new selective kappa…
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1996
1996
Renal and haemodynamic responses to a novel kappa opioid receptor agonist, niravoline (RU 51,599), in rats with cirrhosis
R. Moreau
,
S. Cailmail
,
G. Hamon
,
D. Lebrec
Journal of Gastroenterology and Hepatology
1996
Corpus ID: 25346626
Because renal water retention is a complication of cirrhosis, niravoline (RU 51,599), a novel kappa (κ) opioid receptor agonist…
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1996
1996
Disparate expression of the AVP gene in Sabra hypertension-prone and hypertension-resistant rats.
C. Yagil
,
D. Ben-ishay
,
Y. Yagil
American Journal of Physiology
1996
Corpus ID: 25800302
We recently re-inbred the original colony of SBH-SBN rats, a model of salt-induced hypertension. In the course of phenotyping the…
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