Effect of Niravoline (RU51599), a κ-Opioid Receptor Agonist, on Tumour-Origin Brain Oedema


 Niravoline is a selective κ-opioid receptor agonist. Its effect on tumour-origin brain oedema was investigated in a brain tumour model created by implantation of C6 glioma cells into the brains of Wistar rats. Five weeks after the tumour cell implantation, niravoline was administered iv at 1 mg/kg, a total of four times at one-hour intervals. In the… (More)
DOI: 10.1007/s007010050374


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