nimotuzumab

Known as: Immunoglobulin G1, anti-(humanized mouse monoclonal hR3 beta1 chain anti-human epidermal growth factor receptor), disulfide with humanized mouse monoclonal hR3 kappa-chain, dimer 
A monoclonal antibody being studied in the treatment of some types of cancer. Monoclonal antibodies are made in the laboratory and can locate and… (More)
National Institutes of Health

Papers overview

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2015
2015
PURPOSE A randomised, open label phase III trial was conducted to evaluate efficacy of nimotuzumab, a monoclonal antibody against… (More)
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2014
2014
This multicenter, randomized phase II trial was conducted to compare the efficacy and safety of nimotuzumab plus irinotecan (N… (More)
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2014
2014
Nimotuzumab, a humanized antibody targeting epidermal growth factor receptor, has potent anti-proliferative, anti-angiogenic, and… (More)
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2013
2013
Advanced pancreatic cancer patients have poor prognosis and scarcely respond to conventional therapies. Clinical trials support… (More)
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Highly Cited
2012
Highly Cited
2012
Therapeutic monoclonal antibodies (mAbs) are currently being approved for marketing in Europe and the United States, as well as… (More)
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2012
2012
Epidermal growth factor receptor (EGFR) is suggested to predict the radiosensitivity and/or prognosis of human esophageal… (More)
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Review
2011
Review
2011
INTRODUCTION Diffuse intrinsic pontine gliomas (DIPG) have a poor prognosis: the median survival rate is less than one year… (More)
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Highly Cited
2011
Highly Cited
2011
Nimotuzumab is an EGFR-targeting antibody that has demonstrated encouraging clinical results in the absence of severe side… (More)
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Highly Cited
2009
Highly Cited
2009
Overexpression of the epidermal growth factor (EGF) receptor (EGFR) in cancer cells correlates with tumor malignancy and poor… (More)
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2008
2008
The expression and activity of the epidermal growth factor receptor (EGFR) are determinants of radiosensitivity in several tumour… (More)
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