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neuroendocrine cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A… Expand
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Gene expression profiles of small-cell lung cancers: molecular signatures of lung cancer.
To characterize the molecular mechanisms involved in the carcinogenesis and progression of small-cell lung cancer (SCLC) and… Expand
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2006
2006
Regulation of Secretory Protein Expression in Mature Cells by DIMM, a Basic Helix–Loop–Helix Neuroendocrine Differentiation Factor
During differentiation, neuroendocrine cells acquire highly amplified capacities to synthesize neuropeptides to overcome dilution… Expand
Highly Cited
2004
Highly Cited
2004
Functional diversity of notch family genes in fetal lung development.
In Drosophila, developmental signaling via the transmembrane Notch receptor modulates branching morphogenesis and neuronal… Expand
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Highly Cited
2002
Highly Cited
2002
Different profiles of neuroendocrine cell differentiation evolve in the PC‐310 human prostate cancer model during long‐term androgen deprivation
Neuroendocrine (NE) cells are androgen‐independent cells and secrete growth‐modulating peptide hormones via a regulated secretory… Expand
Highly Cited
2002
Highly Cited
2002
Androgen ablation promotes neuroendocrine cell differentiation in dog and human prostate
Mechanisms triggering prostatic NE differentiation are poorly understood. Since dog and man naturally develop prostatic… Expand
2002
2002
Glucocorticoids induce neuroendocrine cell differentiation and increase expression of N-myc in N-type human neuroblastoma cells.
Human neuroblastoma cell lines comprise cellular counterparts of normal differentiation phenotypes arising from the developing… Expand
2001
2001
Interaction of IGF-binding protein-related protein 1 with a novel protein, neuroendocrine differentiation factor, results in neuroendocrine differentiation of prostate cancer cells.
Neuroendocrine cells have been implicated in many cancers, including small cell lung, cervical, breast, and prostate carcinomas… Expand
1998
1998
Tumor necrosis factor induces neuroendocrine differentiation in small cell lung cancer cell lines.
We studied tumor necrosis factor (TNF)-α as a candidate cytokine to promote neuroendocrine cell differentiation in a nitrosamine… Expand
Highly Cited
1995
Highly Cited
1995
Bombesin and [Leu8]phyllolitorin promote fetal mouse lung branching morphogenesis via a receptor-mediated mechanism.
Pulmonary neuroendocrine cells are localized predominantly at airway branchpoints. Previous work showed that gastrin-releasing… Expand
1991
1991
Gastrin-releasing peptide gene expression in small cell and large cell undifferentiated lung carcinomas.
Gastrin-releasing peptide (GRP; mammalian bombesin) is present in the neuroendocrine cells of human fetal lung and in small cell… Expand
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