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neuroendocrine cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
02419902017

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2007
2007
Notch-1 regulates pulmonary neuroendocrine cell differentiation in cell lines and in transgenic mice.
The notch gene family encodes transmembrane receptors that regulate cell differentiation by interacting with surface ligands on… (More)
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2007
2007
Docetaxel and cisplatin in patients with metastatic androgen independent prostate cancer and circulating neuroendocrine markers.
PURPOSE A link between neuroendocrine cell differentiation and resistance to androgen deprivation has been observed in prostate… (More)
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2006
2006
Regulation of secretory protein expression in mature cells by DIMM, a basic helix-loop-helix neuroendocrine differentiation factor.
During differentiation, neuroendocrine cells acquire highly amplified capacities to synthesize neuropeptides to overcome dilution… (More)
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Highly Cited
2006
Highly Cited
2006
IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.
Neurogenin 3 (Ngn3) is key for endocrine cell specification in the embryonic pancreas and induction of a neuroendocrine cell… (More)
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Highly Cited
2006
Highly Cited
2006
Gene expression profiles of small-cell lung cancers: molecular signatures of lung cancer.
To characterize the molecular mechanisms involved in the carcinogenesis and progression of small-cell lung cancer (SCLC) and… (More)
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Highly Cited
2003
Highly Cited
2003
The bHLH protein Dimmed controls neuroendocrine cell differentiation in Drosophila.
Neuroendocrine cells are specialized to produce, maintain and release large stores of secretory peptides. We show that the… (More)
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2002
2002
Androgen ablation promotes neuroendocrine cell differentiation in dog and human prostate.
BACKGROUND Mechanisms triggering prostatic NE differentiation are poorly understood. Since dog and man naturally develop… (More)
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2002
2002
Neuroendocrine differentiation of human prostatic primary epithelial cells in vitro.
BACKGROUND Dispersed prostatic neuroendocrine cells are involved in growth regulation of the prostate and are considered to play… (More)
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2001
2001
Interaction of IGF-binding protein-related protein 1 with a novel protein, neuroendocrine differentiation factor, results in neuroendocrine differentiation of prostate cancer cells.
Neuroendocrine cells have been implicated in many cancers, including small cell lung, cervical, breast, and prostate carcinomas… (More)
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1998
1998
Tumor necrosis factor induces neuroendocrine differentiation in small cell lung cancer cell lines.
We studied tumor necrosis factor (TNF)-α as a candidate cytokine to promote neuroendocrine cell differentiation in a nitrosamine… (More)
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