nepicastat

Known as: 5-aminomethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphth-2-yl)-1,3-dihydroimidazole-2-thione 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2016
012319972016

Papers overview

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2014
2014
The dopamine-beta-hydroxylase inhibitor nepicastat has been shown to reproduce disulfiram ability to suppress the reinstatement… (More)
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2014
2014
BACKGROUND Recent experimental data indicate that treatment with the selective dopamine β-hydroxylase inhibitor, nepicastat… (More)
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2014
2014
Disulfiram has shown promise as a pharmacotherapy for cocaine dependence in clinical settings, although it has many targets, and… (More)
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2013
2013
Although norepinephrine (NE) does not typically modulate cocaine self-administration under traditional schedules of reinforcement… (More)
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2013
2013
Craving for chocolate is a common phenomenon, which may evolve to an addictive-like behaviour and contribute to obesity… (More)
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2010
2010
The antialcoholism medication disulfiram (Antabuse) inhibits aldehyde dehydrogenase (ALDH), which results in the accumulation of… (More)
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2008
2008
The antialcoholism drug disulfiram has shown recent promise as a pharmacotherapy for treating cocaine dependence, probably via… (More)
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2000
2000
BACKGROUND Inhibition of dopamine beta-hydroxylase (DBH) results in a decrease in norepinephrine synthesis. The present study was… (More)
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1998
1998
Nepicastat (RS-25560-197) is a novel, selective, and potent inhibitor of dopamine beta-hydroxylase, which modulates catecholamine… (More)
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1997
1997
1. Inhibitory modulation of sympathetic nerve function may have a favourable impact on the progression of congestive heart… (More)
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