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nepicastat

Known as: 5-aminomethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphth-2-yl)-1,3-dihydroimidazole-2-thione 
National Institutes of Health

Papers overview

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2015
2015
Abstract 1. This study explores the impact of permeability and P-glycoprotein (P-gp) efflux, upon brain exposure to etamicastat… 
2014
2014
The dopamine‐beta‐hydroxylase inhibitor nepicastat has been shown to reproduce disulfiram ability to suppress the reinstatement… 
2014
2014
BACKGROUND Recent experimental data indicate that treatment with the selective dopamine β-hydroxylase inhibitor, nepicastat… 
Highly Cited
2013
Highly Cited
2013
Although norepinephrine (NE) does not typically modulate cocaine self-administration under traditional schedules of reinforcement… 
2011
2011
Background Human dopamine β-hydroxylase (DBH) is an important therapeutic target for complex traits. Several single nucleotide… 
Highly Cited
2000
Highly Cited
2000
Background—Inhibition of dopamine β-hydroxylase (DBH) results in a decrease in norepinephrine synthesis. The present study was a… 
2000
2000
BACKGROUND Inhibition of dopamine beta-hydroxylase (DBH) results in a decrease in norepinephrine synthesis. The present study was… 
Highly Cited
1997
Highly Cited
1997
1 Inhibitory modulation of sympathetic nerve function may have a favourable impact on the progression of congestive heart failure…