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nepicastat

Known as: 5-aminomethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphth-2-yl)-1,3-dihydroimidazole-2-thione 
 
National Institutes of Health

Papers overview

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2015
2015
The interaction of etamicastat, a novel peripherally acting dopamine-β-hydroxylase (DBH) inhibitor, with the enzyme was studied… Expand
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2015
2015
In the present study, we tested the hypothesis that the potent and selective dopamine-β-hydroxylase (DβH) inhibitor nepicastat… Expand
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2014
2014
The dopamine-beta-hydroxylase inhibitor nepicastat has been shown to reproduce disulfiram ability to suppress the reinstatement… Expand
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2014
2014
BACKGROUND Recent experimental data indicate that treatment with the selective dopamine β-hydroxylase inhibitor, nepicastat… Expand
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2014
2014
Disulfiram has shown promise as a pharmacotherapy for cocaine dependence in clinical settings, although it has many targets, and… Expand
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2013
2013
Although norepinephrine (NE) does not typically modulate cocaine self-administration under traditional schedules of reinforcement… Expand
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2011
2011
BACKGROUND Human dopamine β-hydroxylase (DBH) is an important therapeutic target for complex traits. Several single nucleotide… Expand
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2000
2000
BACKGROUND Inhibition of dopamine beta-hydroxylase (DBH) results in a decrease in norepinephrine synthesis. The present study was… Expand
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2000
2000
Background—Inhibition of dopamine β-hydroxylase (DBH) results in a decrease in norepinephrine synthesis. The present study was a… Expand
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1997
1997
1. Inhibitory modulation of sympathetic nerve function may have a favourable impact on the progression of congestive heart… Expand
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