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negative regulation of transferase activity

Known as: down-regulation of transferase activity, transferase inhibitor, downregulation of transferase activity 
Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

biological control
transferase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Novel histone methyl transferase inhibitor and use thereof
The present invention relates to a novel histone methyl transferase inhibitor. The present invention also relates to a… 
2006
2006
Quantification of farnesylmethylcysteine in lysates of peripheral blood mononuclear cells using liquid chromatography coupled with electrospray tandem mass spectrometry: pharmacodynamic assay for…
Biological effectiveness is an important parameter in determining optimal dosages of molecular targeted drugs, such as farnesyl… 
2005
2005
Nitrogen-containing bisphosphonate incadronate augments the inhibitory effect of farnesyl transferase inhibitor tipifarnib on the growth of fresh and cloned myeloma cells in vitro
RAS gene mutations occur in 30 – 40% of multiple myeloma (MM) patients. Farnesylation is the first step in the post-translational… 
2005
2005
Effect of the Farnesyl Transferase Inhibitor L-744,832 on the Colon Cancer Cell Line DLD-1 and Its Combined Use with Radiation and 5-FU
Background: Ras oncogenes are found in 25% of human tumors and they significantly affect prognosis. One of the major fields… 
2004
2004
Bridgehead modification of trihalocycloheptabenzopyridine leads to a potent farnesyl protein transferase inhibitor with improved oral metabolic stability.
2002
2002
Chiral liquid chromatography separation and chiroptical properties of the enantiomers of dimethyl alpha-hydroxyfarnesylphosphonate, a precursor of a farnesyl protein transferase inhibitor.
Highly Cited
2001
Highly Cited
2001
The farnesyl protein transferase inhibitor SCH66336 is a potent inhibitor of MDR1 product P-glycoprotein.
P-glycoprotein (Pgp)-mediated drug efflux is a major factor contributing to the variance of absorption and distribution of many… 
1996
1996
A simple and efficient synthesis of the ras farnesyl-protein transferase inhibitor chaetomellic acid A.
1991
1991
Mechanisms of the glucose lowering effect of a carnitine palmitoyl transferase inhibitor in normal and diabetic rats.
1979
1979
Effect of intestinal gamma-glutamyl transferase inhibitor on the amount of gamma-glutamyl metabolites in mouse.
Experimental mice fed a balanced rodent chow, called LSM fodder, had markedly lower gamma-glutamyl transferase activity in the… 
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