negative regulation of leucine-tRNA ligase activity

Known as: downregulation of leucine-tRNA ligase activity, downregulation of leucine-tRNA synthetase activity, down-regulation of leucine translase activity 
Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity. [GO_REF:0000059, GOC:TermGenie, PMID… (More)
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Variants in the gene encoding NACHT leucine-rich-repeat protein 1 (NALP1), an important molecule in innate immunity, have… (More)
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2008
2008
Blooms that are formed by cyanobacteria consist of toxic and nontoxic strains. The mechanisms that result in the occurrence of… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Autoimmune and autoinflammatory diseases involve interactions between genetic risk factors and environmental triggers… (More)
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Highly Cited
2007
Highly Cited
2007
Aminoacyl-transfer RNA (tRNA) synthetases, which catalyze the attachment of the correct amino acid to its corresponding tRNA… (More)
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Highly Cited
2003
Highly Cited
2003
Charcot-Marie-Tooth disease type 2D (CMT2D) and distal spinal muscular atrophy type V (dSMA-V) are axonal peripheral neuropathies… (More)
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2002
2002
Mycothiol is a novel thiol produced only by actinomycetes and is the major low molecular weight thiol in mycobacteria. The… (More)
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Highly Cited
2001
Highly Cited
2001
During human immunodeficiency virus type 1 (HIV-1) assembly, tRNA(Lys) isoacceptors are selectively incorporated into virions and… (More)
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Highly Cited
1999
Highly Cited
1999
The prenyltransferase undecaprenyl pyrophosphate synthetase (di-trans,poly-cis-decaprenylcistransferase; EC 2.5.1.31) was… (More)
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Highly Cited
1998
Highly Cited
1998
Cyanophycin (multi-L-arginyl-poly-L-aspartate), a water-insoluble reserve polymer of cyanobacteria, is a product of nonribosomal… (More)
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Highly Cited
1993
Highly Cited
1993
Squalene synthetase (farnesyl diphosphate:farnesyl diphosphate farnesyltransferase; EC 2.5.1.21) is thought to represent a major… (More)
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