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negative regulation of leucine-tRNA ligase activity

Known as: downregulation of leucine-tRNA ligase activity, downregulation of leucine-tRNA synthetase activity, down-regulation of leucine translase activity 
Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity. [GO_REF:0000059, GOC:TermGenie, PMID… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

biological control
leucine-tRNA ligase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Calcium-activated (p)ppGpp Synthetase in Chloroplasts of Land Plants*
The genetic system of chloroplasts, including the machinery for transcription, translation, and DNA replication, exhibits… 
Highly Cited
2006
Highly Cited
2006
The stringent response mediator Rsh is required for Brucella melitensis and Brucella suis virulence, and for expression of the type IV secretion system virB
Physiological adaptation of intracellular bacteria is critical for timely interaction with eukaryotic host cells. One mechanism… 
Highly Cited
2006
Highly Cited
2006
In Vitro Characterization of the Interaction between HIV-1 Gag and Human Lysyl-tRNA Synthetase*
Human immunodeficiency virus type 1 (HIV-1) viral assembly is mediated by multiple protein-protein and protein-nucleic acid… 
Highly Cited
2004
Highly Cited
2004
Cellular Distribution of Lysyl-tRNA Synthetase and Its Interaction with Gag during Human Immunodeficiency Virus Type 1 Assembly
ABSTRACT Lysyl-tRNA synthetase (LysRS) is packaged into human immunodeficiency virus type 1 (HIV-1) via its interaction with Gag… 
Highly Cited
2002
Highly Cited
2002
ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, mycothiol biosynthesis enzyme MshC, is related to class I cysteinyl-tRNA synthetases.
Mycothiol is a novel thiol produced only by actinomycetes and is the major low molecular weight thiol in mycobacteria. The… 
Highly Cited
2001
Highly Cited
2001
Incorporation of Lysyl-tRNA Synthetase into Human Immunodeficiency Virus Type 1
ABSTRACT During human immunodeficiency virus type 1 (HIV-1) assembly, tRNALys isoacceptors are selectively incorporated into… 
Highly Cited
1997
Highly Cited
1997
Human Tyrosyl-tRNA Synthetase Shares Amino Acid Sequence Homology with a Putative Cytokine*
To test the hypothesis that tRNATyr recognition differs between bacterial and human tyrosyl-tRNA synthetases, we sequenced… 
Highly Cited
1996
Highly Cited
1996
Cloning, characterization and disruption of a (p)ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2)
An internal segment of the (p)ppGpp synthetase gene, relA, of Streptomyces coelicolor A3(2) was amplified from genomic DNA using… 
Highly Cited
1994
Highly Cited
1994
Human glycyl-tRNA synthetase. Wide divergence of primary structure from bacterial counterpart and species-specific aminoacylation.
Highly Cited
1988
Highly Cited
1988
Primary structure of a human trifunctional enzyme. Isolation of a cDNA encoding methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase.
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