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negative regulation of NLRP3 inflammasome complex assembly

Known as: down regulation of NALP3 inflammasome complex assembly, inhibition of NLRP3 inflammasome complex assembly, inhibition of NALP3 inflammasome complex assembly 
Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly. [GOC:TermGenie]
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

biological control
down regulation of NLRP3 inflammasome activation

Papers overview

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Highly Cited
2020
Highly Cited
2020
Novel Coronavirus-Induced NLRP3 Inflammasome Activation: A Potential Drug Target in the Treatment of COVID-19
Novel coronaviruses (nCoVs) encode ion-channel proteins called viroporins such as protein E, open reading frame 3a (ORF3a) and… 
Review
2018
Review
2018
NLRP3 inflammasome: Its regulation and involvement in atherosclerosis
Inflammasomes are intracellular complexes involved in the innate immunity that convert proIL‐1β and proIL‐18 to mature forms and… 
Highly Cited
2017
Highly Cited
2017
Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation
The NLRP3 inflammasome is activated in the early period following subarachnoid hemorrhage(SAH), resulting in inflammatory… 
Highly Cited
2016
Highly Cited
2016
Antagonism of the STING Pathway via Activation of the AIM2 Inflammasome by Intracellular DNA
Recent evidence has indicated that innate immune sensing of cytosolic DNA in dendritic cells via the host STING pathway is a… 
Highly Cited
2016
Highly Cited
2016
A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet
The activation of NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome is closely associated with the… 
Highly Cited
2012
Highly Cited
2012
Cutting Edge: Nitric Oxide Inhibits the NLRP3 Inflammasome
Although the NLRP3 inflammasome plays a pivotal role in host defense, its uncontrolled activation is associated with inflammatory… 
Highly Cited
2011
Highly Cited
2011
Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions
In psoriasis, cytosolic DNA in keratinocytes triggers maturation of the cytokine IL-1β via the AIM2 inflammasome. Taking AIM at… 
Highly Cited
2009
Highly Cited
2009
Caspase-7 Activation by the Nlrc4/Ipaf Inflammasome Restricts Legionella pneumophila Infection
Legionella pneumophila (L. pneumophila), the causative agent of a severe form of pneumonia called Legionnaires' disease… 
Highly Cited
2009
Highly Cited
2009
Innate Immunity: Cytoplasmic DNA Sensing by the AIM2 Inflammasome
Highly Cited
2008
Highly Cited
2008
The Nlrp3 inflammasome is critical for aluminium hydroxide‐mediated IL‐1β secretion but dispensable for adjuvant activity
Aluminum hydroxide (alum) is the most widely used adjuvant in human vaccines, but the immune mechanisms that are activated by… 
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