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narlaprevir

National Institutes of Health

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DipeptidesSulfones

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SCH 900518

Papers overview

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2020
2020
Narlaprevir, ritonavir, and sofosbuvir in non-cirrhotic chronic hepatitis C genotype 1 infected patients
2017
2017
Discovery of Boceprevir and Narlaprevir: Ketoamide-Derived HCV NS3 Serine Protease Inhibitors for the Treatment of Chronic Hepatitis C
2016
2016
ЭФФЕКТИВНОСТЬ ЗАТРАТ НА ИНГИБИТОРЫ ПРОТЕАЗЫ ВТОРОЙ ВОЛНЫ ПРИ ТЕРАПИИ ХРОНИЧЕСКОГО ГЕПАТИТА С (1 ГЕНОТИП) У ПАЦИЕНТОВ, НЕ ПОЛУЧАВШИХ РАНЕЕ ПРОТИВОВИРУСНЫЕ ПРЕПАРАТЫ, И ПРИ РЕЦИДИВЕ ЗАБОЛЕВАНИЯ
The protease inhibitors (PI) actively using for the treatment of chronic hepatitis C (CHC). The aim of this analysis was to… 
2014
2014
Computational study on the molecular mechanisms of drug resistance of Narlaprevir due to V36M, R155K, V36M+R155K, T54A, and A156T mutations of HCV NS3/4A protease
Narlaprevir is a novel NS3/4A protease inhibitor of hepatitis C virus (HCV), and it has been tested in a phase II clinical trial… 
2013
2013
Evolutionary dynamics of hepatitis C virus NS3 protease domain during and following treatment with narlaprevir, a potent NS3 protease inhibitor
Narlaprevir, a hepatitis C virus (HCV) NS3/4A serine protease inhibitor, has demonstrated robust antiviral activity in a placebo… 
2012
2012
Insight into the structural requirements of narlaprevir-type inhibitors of NS3/NS4A protease based on HQSAR and molecular field analyses.
In the life cycle of hepatitis C virus (HCV), NS3/NS4A protease has been proved to play a vital role in the replication of the… 
2012
2012
Direct-acting antiviral therapy for chronic hepatitis C
Hepatitis C virus (HCV) infection was discovered in the late 1980s. Since then, tremendous progress has been made in… 
2012
2012
Discovery of Boceprevir and Narlaprevir: The First and Second Generation of HCV NS3 Protease Inhibitors
2012
2012
Discovery of Boceprevir and Narlaprevir: A Case Study for Role of Structure‐Based Drug Design
2010
2010
Gateways to clinical trials.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
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