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naphthyridinomycin

 
National Institutes of Health

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Naphthyridines

Papers overview

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2013
2013
Naphthyridinomycin biosynthesis revealing the use of leader peptide to guide nonribosomal peptide assembly.
Analysis of naphthyridinomycin gene cluster revealed that this antibiotic is generated by nonribosomal peptide synthetase (NRPS… Expand
2012
2012
Hijacking a hydroxyethyl unit from a central metabolic ketose into a nonribosomal peptide assembly line
Nonribosomal peptide synthetases (NRPSs) usually catalyze the biosynthesis of peptide natural products by sequential selection… Expand
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2011
2011
Asymmetric [C + NC + CC] coupling entry to the naphthyridinomycin natural product family: formal total synthesis of cyanocycline A and bioxalomycin β2.
A full account of our [C + NC + CC] coupling approach to the naphthyridinomycin family of natural products is presented… Expand
1994
1994
Structures of dnacin A1 and B1, new naphthyridinomycin-type antitumor antibiotics.
Dnacin A1 and B1 were revealed to be new naphthyridinomycin-type antitumor antibiotics with formulae of C20H23N5O4 and C19H24N4O5… Expand
1991
1991
Computer simulation of the binding of naphthyridinomycin and cyanocycline A to DNA.
Cyanocycline A was found to have a pKa of 6.6. Protonation of N14 was established by 1H NMR spectroscopy. In strongly acidic… Expand
1985
1985
The in vitro interaction of naphthyridinomycin with deoxyribonucleic acids.
The binding of naphthyridinomycin (NAP) to deoxyribonucleic acid was investigated using radioisotope labeled antibiotic… Expand
1985
1985
The total synthesis of (±)-naphthyridinomycin. II. Construction of the pentacyclic carbon skeleton.
Abstract A synthesis of an advanced pentacyclic intermediate to the quinone antibiotic naphthyridinomycin ( 1 ) is described. The… Expand
1982
1982
Naphthyridinomycin, a DNA-reactive antibiotic.
Naphthyridinomycin is a novel quinone antibiotic that is produced in liquid shake cultures by Streptomyces lusitanus… Expand
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1982
1982
Cyanonaphthyridinomycin: a derivative of naphthyridinomycin.
 
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Highly Cited
1975
Highly Cited
1975
Naphthyridinomycin, a new broad-spectrum antibiotic.
A new antibiotic, naphthyridinomycin, was isolated in crystalline form from the culture filtrate of Streptomyces lusitanus AY B… Expand
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