namitecan

Known as: (4S)-11-((E)-((2-Aminoethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2015
01220092015

Papers overview

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2015
2015
Purpose: This is a first-in-human, phase I, dose-escalation study to determine the maximum tolerated dose (MTD) of intravenous… (More)
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2015
2015
AIMS Namitecan is a new camptothecan compound undergoing early clinical development. This study was initiated to build an… (More)
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2014
2014
PURPOSE Despite the frequent overexpression of epidermal growth factor receptor (EGFR) in squamous cell carcinoma (SCC), the… (More)
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2012
2012
Namitecan (ST1968), a novel hydrophilic camptothecin analog of the 7-oxyiminomethyl series, was selected for clinical development… (More)
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2012
2012
The present study aimed to evaluate the new water soluble camptothecin analogue Namitecan (ST1968) in preclinical paediatric… (More)
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Review
2012
Review
2012
Camptothecins are still among the most widely prescribed and effective anticancer drugs. Unfortunately, important drawbacks… (More)
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2011
2011
e13570 Background: Namitecan (N) is a topoisomerase I inhibitor with superior antitumor activity (especially in squamous cell ca… (More)
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2010
2010
ST1968 (namitecan), a novel 7-modified hydrophilic camptothecin, was found to be effective against tumor models relatively… (More)
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2010
2010
The aim of the present study was to extend the use of the "Inverted Chirality Columns Approach (ICCA)" previously developed for… (More)
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2009
2009
2570 Background: Namitecan is a new water-soluble camptothecin analogue which showed high antitumor activity in preclinical… (More)
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