ST 1968

Known as: ST-1968, ST1968 
 
National Institutes of Health

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2015
2015
Purpose: This is a first-in-human, phase I, dose-escalation study to determine the maximum tolerated dose (MTD) of intravenous… (More)
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2015
2015
AIMS Namitecan is a new camptothecan compound undergoing early clinical development. This study was initiated to build an… (More)
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2012
2012
Namitecan (ST1968), a novel hydrophilic camptothecin analog of the 7-oxyiminomethyl series, was selected for clinical development… (More)
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2012
2012
The present study aimed to evaluate the new water soluble camptothecin analogue Namitecan (ST1968) in preclinical paediatric… (More)
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2010
2010
DNA damage response and checkpoint activation are expected to influence the sensitivity to DNA-damaging agents. This study was… (More)
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2010
2010
ST1968 (namitecan), a novel 7-modified hydrophilic camptothecin, was found to be effective against tumor models relatively… (More)
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2010
2010
The aim of the present study was to extend the use of the "Inverted Chirality Columns Approach (ICCA)" previously developed for… (More)
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2009
2009
2570 Background: Namitecan is a new water-soluble camptothecin analogue which showed high antitumor activity in preclinical… (More)
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2008
2008
ST1968, a novel hydrophilic camptothecin analogue of the 7-oxyiminomethyl series, is characterised by the formation of stable DNA… (More)
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2008
2008
ST1968 is a novel hydrophilic camptothecin (CPT) derivative of the 7-oxyiminomethyl series. Because ST1968 retained ability to… (More)
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