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myosin phosphatase activity

Known as: myosin phosphatase, intrinsic catalyst activity 
Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate. [EC:3.1.3.16]
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Targeting by myosin phosphatase‐RhoA interacting protein mediates RhoA/ROCK regulation of myosin phosphatase
Vascular smooth muscle cell contractile state is the primary determinant of blood vessel tone. Vascular smooth muscle cell… 
Highly Cited
2005
Highly Cited
2005
Acute vasodilator effects of a Rho-kinase inhibitor, fasudil, in patients with severe pulmonary hypertension
Pulmonary hypertension (PH) is characterised by progressive elevation of pulmonary artery pressure and pulmonary vascular… 
2004
2004
Telokin mediates Ca2+-desensitization through activation of myosin phosphatase in phasic and tonic smooth muscle
Telokin, a 17 kDa smooth muscle specific protein, consists of the C-terminal domain of MLCK, is phosphorylated by PKA and PKG at… 
Highly Cited
2002
Highly Cited
2002
Phosphorylation of the regulatory subunit of smooth muscle protein phosphatase 1M at Thr850 induces its dissociation from myosin
Highly Cited
2001
Highly Cited
2001
Activation of Myosin Light Chain Phosphatase in Intact Arterial Smooth Muscle During Nitric Oxide-induced Relaxation*
We investigated whether myosin light chain phosphatase activity changes during nitric oxide-induced relaxation of contracted… 
Highly Cited
2001
Highly Cited
2001
Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase targeting subunit and inhibits myosin phosphatase activity
Highly Cited
1999
Highly Cited
1999
Agonist-induced regulation of myosin phosphatase activity in human platelets through activation of Rho-kinase.
Human platelets contained about 15 times lower amounts of Rho-kinase than Ca2+/calmodulin-dependent myosin light chain (MLC… 
Highly Cited
1999
Highly Cited
1999
Rho-associated Kinase of Chicken Gizzard Smooth Muscle*
Rho-associated kinase (Rho-kinase) from chicken gizzard smooth muscle was purified to apparent homogeneity (160 kDa on SDS… 
1995
1995
Polyamines inhibit myosin phosphatase and increase LC20 phosphorylation and force in smooth muscle.
The increase in Ca(2+)-activated force caused by polyamines in beta-escin-permeabilized guinda pig ileum is shown to be… 
1994
1994
Myosin light chain phosphatase activity in ragweed pollen-sensitized canine tracheal smooth muscle.
We have reported that myosin light chain phosphorylation is increased in contracting airway smooth muscle from hyperresponsive… 
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