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mycothiol biosynthetic process
Known as:
mycothiol formation
, mycothiol synthesis
, mycothiol anabolism
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The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D…
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Biochemical studies of inositol N-acetylglucosaminyltransferase involved in mycothiol biosynthesis in Corynebacterium diphtheria.
Yuchuan Guo
,
Lizhen Wang
,
Jiatong Guo
,
Guofeng Gu
,
Zhongwu Guo
Organic and biomolecular chemistry
2017
Corpus ID: 13240128
Mycothiol (MSH) is the predominant low molecular weight thiol produced by actinomycetes, and it plays a pivotal role in the…
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2016
2016
Mycothiol synthesis by an anomerization reaction through endocyclic cleavage
S. Manabe
,
Yukishige Ito
Beilstein Journal of Organic Chemistry
2016
Corpus ID: 2995882
Mycothiol is found in Gram-positive bacteria, where it helps in maintaining a reducing intracellular environment and it plays an…
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2015
2015
Molecular Determinants of N-Acetylglucosamine Recognition and Turnover by N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside Deacetylase (MshB).
Xinyi Huang
,
M. Hernick
Biochemistry
2015
Corpus ID: 25842590
Actinobacteria such as Mycobacterium tuberculosis use the unique thiol mycothiol (MSH) as their primary reducing agent and in the…
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2014
2014
The role of Mycothiol Biosynthesis in Pathogenesis and Drug Susceptibility of Mycobacterium tuberculosis
Xia Xu
2014
Corpus ID: 87149856
2012
2012
Studies in Mycothiol Biosynthesis: Identification, characterization and the in vitro reconstitution of the Mycobacterium tuberculosis pathway enzymes
Lamprecht Da
2012
Corpus ID: 85718883
2011
2011
New synthetic routes to functionalized 2-C-alkylglucosides, precursors of potential inhibitors of mycothiol biosynthesis in the Mycobacteria
F. Muganza
2011
Corpus ID: 94087514
2006
2006
Identification of genes for mycothiol biosynthesis in Streptomyces coelicolor A3(2).
Joo‐Hong Park
,
C. Cha
,
J. Roe
Journal of Microbiology
2006
Corpus ID: 31208195
Mycothiol is a low molecular weight thiol compound produced by a number of actinomycetes, and has been suggested to serve both…
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Highly Cited
2004
Highly Cited
2004
Crystal structure of MshB from Mycobacterium tuberculosis, a deacetylase involved in mycothiol biosynthesis.
A. McCarthy
,
N. A. Peterson
,
Rainer Knijff
,
E. Baker
Journal of Molecular Biology
2004
Corpus ID: 27645493
2003
2003
Solution conformations of mycothiol bimane, 1-D-GlcNAc-alpha-(1 --> 1)-D-myo-Ins and 1-D-GlcNAc-alpha-(1 --> 1)-L-myo-Ins.
J. Mahadevan
,
G. Nicholas
,
C. Bewley
Journal of Organic Chemistry
2003
Corpus ID: 9336498
Mycothiol is an abundant small molecular weight thiol found only in actinomycetes, which include mycobacteria. Mycothiol…
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