morphine-6-glucuronide

Known as: beta-D-Glucopyranosiduronic acid, (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-3-hydroxy-17-methylmorphinan-6-yl, morphine 6 glucuronide, morphine-6beta-glucuronide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2018
010203019732018

Papers overview

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2012
2012
Background and Objective: The analgesic effect of codeine depends on the formation of the opioid metabolites morphine and… (More)
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Highly Cited
2005
Highly Cited
2005
Glucuronidation is a major detoxification pathway for endogenous and exogenous compounds in mammals that results in the… (More)
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Highly Cited
2003
Highly Cited
2003
OBJECTIVE Our objective was to quantify the extent and time course of the effects of morphine-6-glucuronide and morphine on pain… (More)
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Highly Cited
1997
Highly Cited
1997
A human UDP-glucuronosyltransferase (UGT) catalyzing the glucuronidation of morphine has been identified. A full length cDNA was… (More)
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1997
1997
The blood-brain barrier (BBB) permeability to morphine and morphine-6-glucuronide (M6G) is measured under identical conditions… (More)
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1995
1995
1. Morphine 6-glucuronide (M6G) is a metabolite of morphine with analgesic activity. A double-blind, randomised comparison of the… (More)
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1993
1993
Twelve patients with chronic renal failure (dialysis-dependent) and six with good renal function after renal transplantation… (More)
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1992
1992
1. The pharmacokinetics, cardio-respiratory effects and analgesic effects of intravenous morphine-6-glucuronide were studied in… (More)
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1991
1991
Morphine-6-glucuronide is an active metabolite of morphine that has analgesic properties and is measurable in the plasma and… (More)
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1986
1986
Patients with impaired renal function may experience severe and prolonged respiratory depression when treated with morphine. This… (More)
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