montelukast

Known as: (R-(e))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid, Montélukast, montelukast [Chemical/Ingredient] 
The active ingredient in a drug used to treat symptoms of asthma, such as trouble breathing, tight chest, wheezing, coughing, and runny nose… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
05010019952017

Papers overview

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Highly Cited
2006
Highly Cited
2006
RATIONALE Interpatient variability in montelukast response may be related to variation in leukotriene pathway candidate genes… (More)
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Highly Cited
2005
Highly Cited
2005
The PREVIA study was designed to investigate the role of montelukast, a leukotriene receptor antagonist, in the prevention of… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Eosinophilic oesophagitis is a rarely diagnosed condition involving eosinophil infiltration of the oesophageal mucosa… (More)
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Highly Cited
2002
Highly Cited
2002
Leukotriene antagonists block the proinflammatory actions of leukotrienes (LT) and have been introduced as new treatments for… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The greatest prevalence of asthma is in preschool children; however, the clinical utility of asthma therapy for this… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Oral leukotriene receptor antagonists have been shown to have efficacy in chronic asthma. OBJECTIVE To compare the… (More)
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE To determine the ability of montelukast, a leukotriene receptor antagonist, to allow tapering of inhaled… (More)
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Highly Cited
1999
Highly Cited
1999
Leukotrienes are pro-inflammatory mediators which may contribute to tissue, sputum, and blood eosinophilia seen in allergic and… (More)
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Highly Cited
1998
Highly Cited
1998
CONTEXT Leukotrienes are important mediators of asthma by causing bronchoconstriction, mucous secretion, and increased vascular… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Patients with mild asthma frequently have only exercise-induced bronchoconstriction, a symptom of inadequate control… (More)
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