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montelukast

Known as: (R-(e))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid, Montélukast, montelukast [Chemical/Ingredient] 
The active ingredient in a drug used to treat symptoms of asthma, such as trouble breathing, tight chest, wheezing, coughing, and runny nose… 
National Institutes of Health

Related topics

Related topics

17 relations

Broader (6)

AcetatesAcetic Acid EstersAnti-Asthmatic AgentsCytochrome P-450 CYP1A2 Inducers
AsthmaCYP2C9 protein, humanDrug AllergyRhinitis, Allergic, Perennial

Narrower (2)

MK 0476Singulair

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Improvement of hepatic fibrosis by leukotriene inhibition in cholestatic rats.
Highly Cited
2008
Highly Cited
2008
Effects of exercise training and montelukast in children with mild asthma.
PURPOSE Data from the general population suggest that habitual exercise decreases bronchial responsiveness, but the possible role… 
2008
2008
Cultured CD4T cells and primary human lymphocytes express hOATPs: intracellular accumulation of saquinavir and lopinavir
Drug efflux tranporters (P‐glycoprotein (P‐gp), multidrug resistance‐associated protein (MRP)) limit the cellular uptake of human… 
Highly Cited
2006
Highly Cited
2006
Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction.
Highly Cited
2004
Highly Cited
2004
No effect of montelukast on asthma‐like symptoms in elite ice hockey players
Background:  Controlled clinical trials on the effects of leukotriene antagonists on asthma‐like symptoms, bronchial… 
Highly Cited
2003
Highly Cited
2003
Effects of mediator antagonism on mannitol and adenosine monophosphate challenges
Background Airway hyper‐responsiveness (AHR) to indirect stimuli is a useful non‐invasive surrogate inflammatory marker in the… 
Review
2003
Review
2003
Prospects for antihistamines in the treatment of asthma.
Highly Cited
2002
Highly Cited
2002
Inhaled corticosteroids plus salmeterol or montelukast: effects on resource utilization and costs.
BACKGROUND Experimental clinical studies have demonstrated that the addition of salmeterol to inhaled corticosteroids (ICSs) is… 
Highly Cited
2001
Highly Cited
2001
Montelukast and Churg-Strauss syndrome.
I read with interest the case report by Tuggey and Hosker where Churg-Strauss syndrome was associated with the use of montelukast… 
Highly Cited
2001
Highly Cited
2001
CASE REPORT: Use of Montelukast as Steroid-Sparing Agent for Recurrent Eosinophilic Gastroenteritis
Patients with eosinophilic gastroenteritis generally respond well to corticosteroids but relapses are common. Patients with… 
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