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monoclonal antibody HeFi-1

Known as: HeFi-1, MOAB HeFi-1 
A murine monoclonal antibody with potential antineoplastic activity. Monoclonal antibody HeFi-1 binds to CD30, a cell surface antigen found on… 
National Institutes of Health

Related topics

Related topics

8 relations
B-LymphocytesInhibition of Cell ProliferationMetastasis SuppressionReed-Sternberg Cells

Broader (1)

Monoclonal Antibodies

Papers overview

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2005
2005
CD30 as Target for Radioimmunotherapy (RIT) of Lymphoma.
Objectives: CD30 is overexpressed on the cell surface by a variety of malignant diseases including Hodgkin’s lymphoma (HL). It is… 
2004
2004
Increased Expression and Activation of CD30 Induce Apoptosis in Human Blood Eosinophils1
Eosinophils are one of the major effector cells in asthma, and controlling the number and survival of eosinophils might attenuate… 
2003
2003
Proliferation of CD30+ T-helper 2 lymphoma cells can be inhibited by CD30 receptor cross-linking with recombinant CD30 ligand.
PURPOSE Cutaneous anaplastic large cell lymphomas (ALCLs) are characterized by the expression of CD30, spontaneous regression of… 
2003
2003
Proliferation of CD 30 T-Helper 2 Lymphoma Cells Can Be Inhibited by CD 30 Receptor Cross-Linking with Recombinant CD 30 Ligand 1
Purpose: Cutaneous anaplastic large cell lymphomas (ALCLs) are characterized by the expression of CD30, spontaneous regression of… 
2000
2000
Characterization of the CD30L binding domain on the human CD30 molecule using anti-CD30 antibodies.
CD30 and its counter-receptor CD30 ligand (CD30L) are members of the TNF-receptor/TNFalpha superfamily and function to regulate… 
1989
1989
Characterization of Hodgkin's disease derived cell line HDLM-2.
The cell line HDLM-2 was established from the pleural effusion of a patient with Hodgkin's disease. Here, we describe the… 
1987
1987
Effect of monoclonal antibodies anti-2H9, anti-IRac, and anti-HeFi-1 on the surface antigens of Reed-Sternberg cells.
The interaction of 3 monoclonal antibodies (MAbs)--anti-HeFi-1, anti-2H9, and anti-IRac--with Reed-Sternberg (RS) cells was… 
1987
1987
The H-RS-like cells in infectious mononucleosis are transformed interdigitating reticulum cells.
The lymphoid tissues from patients with infectious mononucleosis or, less frequently, with other reactive conditions may contain… 
1986
1986
Monoclonal antibodies against SU-DHL-1 cells stain the neoplastic cells in true histiocytic lymphoma, malignant histiocytosis, and Hodgkin's disease.
Three murine monoclonal antibodies, named 2H9, 1E9 and 1A2, were produced after immunization of BALB/c mice with cells of the SU… 
1986
1986
Phenotypes and phorbol ester-induced differentiation of human histiocytic lymphoma cell lines (U-937 and SU-DHL-1) and Reed-Sternberg cells.
Hodgkin's mononuclear cells, Reed-Sternberg (H-RS) cells, and U-937 and SU-DHL-1 histocytic cell lines were induced to… 
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