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mitonafide

Known as: 2-(2-(dimethylamino)ethyl)-5-nitro-1H-benz(de)isoquinoline-1,3(2H)-dione, N-(2-dimethylaminoethyl)-3-nitro-naphthalimide, N-(2-dimethylaminoethyl)-3-nitronaphthalimide 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Antineoplastic AgentsAntiviral AgentsIntercalating AgentsNaphthalimides

Narrower (1)

M 4212

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Determination of formaldehyde in single cell by capillary electrophoresis with LIF detection
As a small molecule gas, formaldehyde (FA) is the simplest carbonyl active material and plays an important role in the carbon… 
2017
2017
Bulky 4,6-disubstituted tetraphenylethene-naphthalimide dyad: synthesis, copolymerization, stimuli-responsive fluorescence and cellular imaging.
We report the design and synthesis of a tetraphenylethene substituted with naphthalimide at the 4, 6 positions, named NI-2TPE. NI… 
2015
2015
New photostable naphthalimide-based fluorescent probe for mitochondrial imaging and tracking.
2010
2010
Investigations on the use of fluorescence dyes for labeling dendrimers: cytotoxicity, accumulation kinetics, and intracellular distribution.
Fluorescent dyes (e.g., dansyl, fluoresceine isothiocyanate, or naphthalimide groups) are widely used as markers to study… 
2005
2005
Benzamide and 4‐amino 1,8 naphthalimide treatment inhibit telomerase activity by down‐regulating the expression of telomerase associated protein and inhibiting the poly(ADP‐ribosyl)ation of…
To test the role of poly(ADP‐ribose) polymerase on the telomerase activity, we determined the telomerase activity in leukemic… 
2004
2004
Phase I study of mitonafide with a 3-day administration schedule: Early interruption due to severe central nervous system toxicity
SummaryEleven patients with solid tumors for whom effective therapy was not available entered a phase I study of mitonafide given… 
1999
1999
Dimeric analogues of non-cationic tricyclic aromatic carboxamides are a new class of cytotoxic agents.
A series of tricyclic aromatic carboxamides, and their corresponding dimeric analogues, were prepared and their growth-inhibitory… 
1996
1996
Synthesis, Structure and Antitumor Activity of New Benz(d,e) isoquinoline‐1,3‐diones
1992
1992
Phase I study of mitonafide in 120 hour continuous infusion in non-small cell lung cancer
SummaryMitonafide is the lead compound of a new series of antitumor drugs, the 3-Nitronaphthalimides, which have shown… 
1984
1984
Identification of the specific sites of interaction between intercalating drugs and DNA.
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