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mitonafide

Known as: 2-(2-(dimethylamino)ethyl)-5-nitro-1H-benz(de)isoquinoline-1,3(2H)-dione, N-(2-dimethylaminoethyl)-3-nitro-naphthalimide, N-(2-dimethylaminoethyl)-3-nitronaphthalimide 
 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Antineoplastic AgentsAntiviral AgentsIntercalating AgentsNaphthalimides

Narrower (1)

M 4212

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A novel dithiourea-appended naphthalimide "on-off" fluorescent probe for detecting Hg2+ and Ag+ and its application in cell imaging.
An effective dithiourea-appended 1,8-naphthalimide fluorescent probe was designed and synthesized. This probe could recognize Hg2… Expand
2016
2016
Visualizing Hydrogen Sulfide in Mitochondria and Lysosome of Living Cells and in Tumors of Living Mice with Positively Charged Fluorescent Chemosensors.
Two fluorescent chemosenors, Mito-HS and Lyso-HS, were rationally designed and synthesized with positive charge at physiological… Expand
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2015
2015
New photostable naphthalimide-based fluorescent probe for mitochondrial imaging and tracking.
Monitoring mitochondria morphological changes temporally and spatially exhibits significant importance for diagnosing, preventing… Expand
2014
2014
A ratiometric fluorescent probe for the detection of hydroxyl radicals in living cells.
A naphthalimide-naphthyridine derivative has been synthesized for the detection of hydroxyl radicals. It can distinguish hydroxyl… Expand
2012
2012
3-Nitro-naphthalimide and nitrogen mustard conjugate NNM-25 induces hepatocellular carcinoma apoptosis via PARP-1/p53 pathway
Hepatocellular carcinoma (HCC) is one of the main causes of death in cancer. Some naphthalimide derivatives exert high anti… Expand
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2009
2009
Neuroprotective potential of combination of resveratrol and 4-amino 1,8 naphthalimide in experimental diabetic neuropathy: Focus on functional, sensorimotor and biochemical changes
The present study investigated whether combination of resveratrol and 4-amino 1,8 naphthalimide (4-ANI) is effective in the… Expand
2008
2008
Design, synthesis, and biological evaluation of new mitonafide derivatives as potential antitumor drugs.
A series of potential DNA-binding antitumor agents, 2-[omega-(alkylamino)alkyl]-6-{[omega-(alkylamino)alkyl]amino}-1H-benzo[de… Expand
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Highly Cited
2007
Highly Cited
2007
A naphthalimide-calixarene as a two-faced and highly selective fluorescent chemosensor for Cu2+ or F-
Abstract A new naphthalimide–calix[4]arene was synthesized as a two-faced and highly selective fluorescent chemosensor for Cu 2… Expand
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2005
2005
Benzamide and 4‐amino 1,8 naphthalimide treatment inhibit telomerase activity by down‐regulating the expression of telomerase associated protein and inhibiting the poly(ADP‐ribosyl)ation of…
To test the role of poly(ADP‐ribose) polymerase on the telomerase activity, we determined the telomerase activity in leukemic… Expand
Highly Cited
1989
Highly Cited
1989
Topoisomerase II-mediated DNA cleavage by amonafide and its structural analogs.
Treatment of SV40-infected monkey cells with amonafide (benzisoquinolinedione), an intercalative antitumor drug, resulted in… Expand
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