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mitogen-activated protein kinase p38

Known as: Protein Kinase, p38, p38 Mitogen-Activated Protein Kinases, p38 Protein Kinase 
A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including CELL GROWTH PROCESSES; CELL DIFFERENTIATION… 
National Institutes of Health

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In BloodMAP kinase activityMAP3K8 protein, humanMAPK11 gene

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MAPK14 protein, human

Papers overview

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2015
2015
Activation of Type 4 Metabotropic Glutamate Receptor Attenuates Oxidative Stress-Induced Death of Neural Stem Cells with Inhibition of JNK and p38 MAPK Signaling.
Promoting both endogenous and exogenous neural stem cells' (NSCs) survival in the hostile host environments is essential to cell… 
2007
2007
Pathophysiological role of the activation of p38 mitogen‐activated protein kinases in poorly differentiated gastric cancer
p38 mitogen‐activated protein kinases (MAPK) contribute to the loss of cell–cell contact and the round cell shape characteristic… 
2006
2006
NPC1 Gene Deficiency Leads to Lack of Neural Stem Cell Self‐Renewal and Abnormal Differentiation Through Activation of p38 Mitogen‐Activated Protein Kinase Signaling
Neural stem cells (NSCs) are capable of giving rise to neurons, glia, and astrocytes. Although self‐renewal and differentiation… 
2006
2006
The Tyrosine Kinase Syk Regulates TPL2 Activation Signals*
Tpl2/Cot is a serine/threonine kinase that plays a key physiological role in the regulation of immune responses to pro… 
2004
2004
Induction of cyclooxygenase-2 expression in human tracheal smooth muscle cells by interleukin-1beta: involvement of p42/p44 and p38 mitogen-activated protein kinases and nuclear factor-kappaB.
Interleukin-1beta (IL-1beta) has been recognized as a potent stimulus for the synthesis of prostaglandin (PG), which has been… 
2004
2004
Active stress kinase p38 enhances and perpetuates abnormal tau phosphorylation and deposition in Pick’s disease
Abnormal tau hyperphosphorylation and deposition in Pick bodies is a major abnormality in Pick’s disease (PiD). This is… 
2003
2003
Exposure to Asphalt Fumes Activates Activator Protein-1 through the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway in Mouse Epidermal Cells*
Occupational exposure to asphalt fumes may pose a health risk. Experimental studies using animal and in vitro models indicate… 
1999
1999
Distinct roles for p42/p44 and p38 mitogen-activated protein kinases in the induction of IL-2 by IL-1.
Interleukin 1 (IL-1) activates p42/p44 and p38 mitogen-activated protein kinases (MAP kinases) in target cells. Here we have used… 
Highly Cited
1998
Highly Cited
1998
Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression*
The exact mechanism of the spatial organization of the insulin signaling pathway leading to nuclear events remains unknown. Here… 
Highly Cited
1997
Highly Cited
1997
Hypertonic saline activates protein tyrosine kinases and mitogen-activated protein kinase p38 in T-cells.
OBJECTIVES In previous in vitro studies, we have found that hypertonic saline (HTS) can augment T-cell proliferation and restore… 
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