mitochondria-nucleus signaling pathway

Known as: mitochondrial signaling pathway, retrograde response, mitochondria-nucleus signal transduction 
A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal.
Impaired insulin and IGF-1 signaling (iIIS) in C. elegans daf-2 mutants extends life span more than 2-fold. Constitutively, iIIS… (More)
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Review
2012
Review
2012
Mitochondrial signaling contributes to disuse muscle atrophy.
It is well established that long durations of bed rest, limb immobilization, or reduced activity in respiratory muscles during… (More)
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Review
2010
Review
2010
Mitochondrial signaling in cell death via the Bcl-2 family.
Apoptosis is a critical process for the maintenance of tissue homeostasis and prevention of tumorigenesis. The members of the Bcl… (More)
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Highly Cited
2010
Highly Cited
2010
Kaempferol induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS cells.
Kaempferol is a natural flavonoid. Previous studies have reported that kaempferol has anti-proliferation activities and induces… (More)
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2010
2010
Curcumin induces apoptosis in human lung adenocarcinoma A549 cells through a reactive oxygen species-dependent mitochondrial signaling pathway.
Several studies have shown that curcumin can induce apoptosis and inhibit growth in human A549 lung adenocarcinoma cells. However… (More)
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Review
2004
Review
2004
Mitochondrial signaling: the retrograde response.
Mitochondrial retrograde signaling is a pathway of communication from mitochondria to the nucleus that influences many cellular… (More)
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Highly Cited
2004
Highly Cited
2004
Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy.
Photobiomodulation by light in the red to near infrared range (630-1000 nm) using low energy lasers or light-emitting diode (LED… (More)
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Highly Cited
2002
Highly Cited
2002
The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.
The SAGA complex is a conserved histone acetyltransferase-coactivator that regulates gene expression in Saccharomyces cerevisiae… (More)
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Highly Cited
2000
Highly Cited
2000
Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p.
Cells modulate the expression of nuclear genes in response to changes in the functional state of mitochondria, an interorganelle… (More)
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Highly Cited
1999
Highly Cited
1999
Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae.
Replicative capacity, which is the number of times an individual cell divides, is the measure of longevity in the yeast… (More)
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