Functional analysis of the Saccharomyces cerevisiae YFR021w/YGR223c/YPL100w ORF family suggests relations to mitochondrial/peroxisomal functions and amino acid signalling pathways.

@article{Georgakopoulos2001FunctionalAO,
  title={Functional analysis of the Saccharomyces cerevisiae YFR021w/YGR223c/YPL100w ORF family suggests relations to mitochondrial/peroxisomal functions and amino acid signalling pathways.},
  author={Tassos Georgakopoulos and George Koutroubas and Ioannis Vakonakis and M. Tzermia and Vassiliki Prokova and Alexandra Voutsina and Despina Alexandraki},
  journal={Yeast},
  year={2001},
  volume={18 12},
  pages={1155-71}
}
Saccharomyces cerevisiae YFR021w, YGR223c and YPL100w are paralogous ORFs of unknown function. Phenotypic analysis of overexpression, single-, double- and triple-ORF deletion strains under various growth conditions indicated mitochondria-related functions for all three ORFs. Two-hybrid screens of a yeast genomic library identified potentially interacting… CONTINUE READING