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metioprim

Known as: 2,4-diamino-5-[3,5-dimethoxy-4-(methyltbio)benzyl]pyrimidine, 5-((3,5-dimethoxy-4-(methylthio)phenyl)methyl)-2,4-pyrimidinediamine, methioprim 
National Institutes of Health

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Broader (1)

Trimethoprim
analogs & derivatives

Papers overview

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2009
2009
Trimethoprim, metioprim, tetroxoprim, and RO 10-5970 in canine bone.
The penetration of trimethoprim and three derivatives into bone tissue was investigated in a dog model. Our data demonstrated… 
1987
1987
Pharmacokinetics and metabolism of metioprim in pigs and goats.
The pharmacokinetics and metabolism of metioprim (MTP) have been studied after intravenous administration of a single dose of 5… 
1986
1986
Human pharmacokinetics and skin blister levels of sulfonamides and dihydrofolate reductase inhibitors.
The penetration into suction skin blisters and pharmacokinetics of 4 sulfonamides (sulfacarbamide, sulfadimidine, sulfadiazine… 
1984
1984
Diffusion of metioprim, tetroxoprim and sulphadiazine in the cerebrospinal fluid of dogs with healthy meninges and dogs with experimental meningitis.
The diffusion of metioprim (MTP), tetroxoprim (TXP) and sulphadiazine (SDZ) in cerebrospinal fluid (CSF), following single… 
1983
1983
Bacterial growth kinetics of Escherichia coli and mycobacteria in the presence of brodimoprim and metioprim alone and in combination with sulfamerazine and dapsone (VI).
Bacterial growth kinetics and checkerboard titration experiments have been performed to determine the inhibitory power of… 
1983
1983
Activity of Brodimoprim and Metioprim Alone and in Combination with Sulfonamides Against Anaerobic Bacteria
The activities of the 2,4-diamino-5-benzylpyrimidines brodimoprim and metioprim against anaerobic bacteria were tested alone and… 
1983
1983
Pharmacokinetics of methioprim in human volunteers.
The pharmacokinetics of methioprim have been studied in 11 healthy volunteers who received tablets of 320 mg as a first dose… 
1983
1983
Pharmacokinetics of metioprim in normal subjects and patients with impaired renal function
The pharmacokinetics of metioprim, a new competitive inhibitor of bacterial dihydrofolate reductases, were studied after a single… 
1982
1982
[Antibacterial activity of 2 trimethoprim analogs (methioprim, brodimoprim) on recently isolated Shigella].
1959
1959
Metabolic Alteration of 2-Methylthio-4-Amino-5-Hydroxymethylpyrimidine (Methioprim).∗ †
Summary Rat liver slices convert methioprim to 2-methylthio-4-amino-5-formylpyrimidine and 2-methylthio-4-amino-5-pyrimidine… 
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