methyl pyruvate

 

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Topic mentions per year

1967-2017
02419672017

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2014
2014
BACKGROUND Amyotrophic lateral sclerosis (ALS) is a disease caused by motor neuron degeneration. Recently, a novel SIGMAR1 gene… (More)
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2013
Highly Cited
2013
Facilitated pyruvate transport across the mitochondrial inner membrane is a critical step in carbohydrate, amino acid, and lipid… (More)
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2011
Highly Cited
2011
Tumor cell proliferation requires both growth signals and sufficient cellular bioenergetics. The AMP-activated protein kinase… (More)
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2004
Highly Cited
2004
Glucose-stimulated insulin secretion is a multistep process dependent on beta-cell metabolic flux. Our previous studies on intact… (More)
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2002
2002
In pancreatic beta-cells, methyl pyruvate is a potent secretagogue and is widely used to study stimulus-secretion coupling. In… (More)
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2001
2001
The role of mitochondria in stimulus-secretion coupling of pancreatic beta-cells was examined using methyl pyruvate (MP). MP… (More)
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1997
1997
The methyl ester of pyruvic acid (methyl pyruvate) stimulated a dose-dependent increase in insulin secretion from isolated… (More)
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1996
1996
The metabolism of methyl pyruvate was compared to that of pyruvate in isolated rat pancreatic islets. Methyl pyruvate was found… (More)
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1996
1996
Methyl pyruvate was found to exert a dual effect on insulin release from isolated rat pancreatic islets. A positive… (More)
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1995
1995
Methyl pyruvate, when tested at a 10mM concentration, caused a rapid and sustained increase of insulin release evoked by either 7… (More)
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