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methionine-enkephalin receptor

Known as: opioid growth factor receptor, met-enkephalin receptors, enkephalin, Met(5)-Arg(6)-Phe(7) receptor 
National Institutes of Health

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4 relations
OGFR geneOGFRL1 geneOpioid Growth Factor Receptor, human

Broader (1)

Opioid Receptor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Exogenous OGF enhances the anti-tumor activity of cisplatin on hepatocellular carcinoma.
BACKGROUND Hepatocellular carcinoma results in high cancer mortality and is difficult to eradicate because of its late stage at… 
2010
2010
Internalization of the opioid growth factor, [Met5]-enkephalin, is dependent on clathrin-mediated endocytosis for downregulation of cell proliferation.
The opioid growth factor (OGF; [Met(5)]-enkephalin), a constitutively expressed and tonically active inhibitory peptide… 
2010
2010
Abstract 697: Inhibition of Cancer Progression by Upregulation of the Opioid Growth Factor (OGF) - OGF Receptor (OGFr) Axis Using Imquimod or Low Dose Naltrexone
Opioid growth factor (OGF, [Met5] enkephalin), is a tonically active, negative growth factor, and interacts with a nuclear… 
2010
2010
Abstract 4153: Short term opioid receptor blockade inhibits cancer cell proliferation independent of immune function by upregulation of the OGF-OGFr axis: A tissue culture model of low dose…
Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC The opioid growth factor (OGF) is an autocrine… 
2008
2008
Expression of opioid growth factor (OGF)-OGF receptor (OGFr) axis in human nonmedullary thyroid cancer.
BACKGROUND Although thyroid cancers are readily treatable with surgery and radioactive iodine, there are problems in managing… 
2007
2007
Overexpression of the opioid growth factor receptor downregulates cell proliferation of human squamous carcinoma cells of the head and neck.
The opioid growth factor (OGF) is a constitutively expressed negative growth regulator whose action is mediated by the OGF… 
2007
2007
Overexpression of the opioid growth factor receptor potentiates growth inhibition in human pancreatic cancer cells.
The opioid growth factor (OGF), [Met5]-enkephalin, and OGF receptor (OGFr) form an inhibitory axis regulating the growth of human… 
2004
2004
Opioid growth factor (OGF) inhibits anchorage-independent growth in human cancer cells.
Opioid growth factor (OGF) is a native endogenous opioid peptide ([Met5]-enkephalin) that interacts with the OGF receptor (OGFr… 
2004
2004
Gene expression of OGFr in the developing and adult rat brain and cerebellum
2003
2003
The expression and function of the OGF–OGFr axis – a tonically active negative regulator of growth – in COS cells
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